Results 61 to 70 of about 366,377 (310)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Experiment and Crystal Plasticity Simulation of Forming Limit of Quenching Partitioning Steel

open access: yesShanghai Jiaotong Daxue xuebao
Quenching-partitioning (QP) steel combines ultrahigh strength with good ductility due to the martensitic transformation during plastic deformation. However, the formability of the QP1180 steel remains unclear.
YANG Hao, TANG Weiqin
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Applications forming limit diagrams

open access: yes, 2011
Thesis contains an overview of four types of forming limit diagrams which includes Keeler-Goodwin diagrams, diagrams of ultimate degree of deformation, diagrams of limit plasticity and deformation-mechanism maps.
Smrž, Peter
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Forming Limit of Holed Dome in Two-Stage Stretch Forming

open access: yes, 2010
This paper deals with the accurate prediction of forming limit of a dome with a circular hole in two-stage stretch forming. Since this two-stage forming is a process of non-proportional deformation, a fracture criterion, which is capable to predict ...
Ryutaro Hino   +2 more
core   +1 more source

RESEARCH ON THE FORMING LIMIT OF INCREMENTAL THERMAL FORMING OF MAGNESIUM ALLOY SHEET HEATED BY LIQUID MEDIUM

open access: yesJixie qiangdu, 2018
Forming limit is an important performance index and process parameter in sheet metal processing. In this paper,A method for the thermal incremental forming of liquid while supporting and heating was proposed.
SHI PengTao   +3 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Stress-based forming limit curves

open access: yes, 2023
Stress-based forming limit ...
T Stoughton (13452321)   +1 more
core  

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