Results 61 to 70 of about 366,377 (310)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Experiment and Crystal Plasticity Simulation of Forming Limit of Quenching Partitioning Steel
Quenching-partitioning (QP) steel combines ultrahigh strength with good ductility due to the martensitic transformation during plastic deformation. However, the formability of the QP1180 steel remains unclear.
YANG Hao, TANG Weiqin
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Applications forming limit diagrams
Thesis contains an overview of four types of forming limit diagrams which includes Keeler-Goodwin diagrams, diagrams of ultimate degree of deformation, diagrams of limit plasticity and deformation-mechanism maps.
Smrž, Peter
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Forming Limit of Holed Dome in Two-Stage Stretch Forming
This paper deals with the accurate prediction of forming limit of a dome with a circular hole in two-stage stretch forming. Since this two-stage forming is a process of non-proportional deformation, a fracture criterion, which is capable to predict ...
Ryutaro Hino +2 more
core +1 more source
Forming limit is an important performance index and process parameter in sheet metal processing. In this paper,A method for the thermal incremental forming of liquid while supporting and heating was proposed.
SHI PengTao +3 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Stress-based forming limit curves
Stress-based forming limit ...
T Stoughton (13452321) +1 more
core

