Research on the integral forming process of thin walled and thick mouth seamless gas cylinders. [PDF]
Sci Rep, 2023 Wang C +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Engineering the structural and electrical interplay of nanostructured Au resistive switching networks by controlling the forming process. [PDF]
Sci Rep, 2023 Nadalini G +5 more
europepmc +1 more source
Abstract This chapter presents a view of the process of dreaming as a narrative activity, within a view of narrative cognition as categorically distinct from the immediacy of phenomenal encounter. Dreaming does not conform to the enactive reciprocity between agent and environment assumed by predictive processing, but instead involves ...
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Experimental Research and Numerical Modelling of the Cold Forming Process of the Inconel 625 Alloy Sheets Using Flexible Punch. [PDF]
Materials (Basel), 2023 Balcerzak M +6 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Modeling and Experimental Investigation of U-R Relationship of AA6061-T6 Tubes Manufactured via Free Bending Forming Process. [PDF]
Materials (Basel), 2023 Abd El-Aty A +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Study of the Gelatin Low-Temperature Deposition Manufacturing Forming Process Based on Fluid Numerical Simulation. [PDF]
Foods, 2023 Tong Q, Zhao W, Guo T, Wang D, Dong X.
europepmc +1 more source