FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Characterization of Hexagonal Close-Packed Zn-Cu-Ti Alloy Pyramid Drawpieces in Single-Point Incremental Sheet Forming Process. [PDF]
Materials (Basel)Kuczek Ł +4 more
europepmc +1 more source
Minimizing the Main Strains and Thickness Reduction in the Single Point Incremental Forming Process of Polyamide and High-Density Polyethylene Sheets. [PDF]
Materials (Basel), 2023 Rosca N +6 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Deformational Analysis of a Titanium Alloy Supported by the Mathematical Modelling of the Sheet Metal Forming Process via Numerical Simulation. [PDF]
Materials (Basel)Koreček D, Solfronk P, Sobotka J.
europepmc +1 more source
Multistage Tool Path Optimisation of Single-Point Incremental Forming Process. [PDF]
Materials (Basel), 2021 Yan Z +7 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Research Trends in Isothermal Near-Net-Shape Forming Process of High-Performance Titanium Alloys. [PDF]
Materials (Basel)Chu S +5 more
europepmc +1 more source
Experimental Research on Variable Parameter Forming Process for Forming Specimen of TC4 Titanium Alloy by Selective Laser Melting. [PDF]
Materials (Basel), 2022 Liu Y +5 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source