COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Optimization of electromagnetic forming process parameters for curved specimens based on CCD-RSM. [PDF]
Sci RepTang J, Li M, Wang T.
europepmc +1 more source
Investigation of Pre-Aged Hardening Single-Point Incremental Forming Process and Mechanical Properties of AA6061 Aluminum Alloy. [PDF]
Materials (Basel), 2023 Zhang Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Investigation of manufacturing bilayer gears using flow forming process to enhance the strength of gears. [PDF]
Sci RepKhodadadi M.
europepmc +1 more source
Accurate Flow Characterization of A6082 for Precision Simulation of a Hot Metal Forming Process. [PDF]
Materials (Basel), 2022 Park JH, Ji SM, Choi JM, Joun MS.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Study on Winding Forming Process of Glass Fiber Composite Pressure Vessel. [PDF]
Materials (Basel)Wu R, Zeng W, Li F, Tian H, Li X.
europepmc +1 more source
Experimental Research on Wolfram Inert Gas AA1050 Aluminum Alloy Tailor Welded Blanks Processed by Single Point Incremental Forming Process. [PDF]
Materials (Basel), 2023 Rusu GP +4 more
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source