Results 191 to 200 of about 1,164,003 (317)

Numerical Study on Electromagnetic Hydraulic Forming Process to Overcome Limitations of Electromagnetic Forming Process. [PDF]

Materials (Basel)
Kim YB, Kim J.
europepmc   +1 more source

Investigation of Advanced Robotized Polymer Sheet Incremental Forming Process. [PDF]

Sensors (Basel), 2021
Ostasevicius V, Eidukynas D, Jurenas V, Paleviciute I, Gudauskis M, Grigaliunas V.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Investigation of feeding devices and development of design considerations for a new feeder for micro-sheet forming

, 2008
Recent review in micro-forming research and technological development suggested that the trend of the development is more focused on the manufacturing processes, machines and tooling, and efforts on the methods and systems for integrated precision ...
Brockett, Andrew, Qin, Yi, Harrison, Colin, Razali, Akhtar   +3 more
core  

Study on the Damage Mechanisms in the Forming Process of High-Strength Steel Laser Tailor Welded Blanks Based on the Johnson-Cook Damage Model. [PDF]

Materials (Basel)
Sun X, Li H, Gao S, Li Q.
europepmc   +1 more source

Understanding Effects of Ultrasonic Vibration on Microstructure Evolution in Hot Forming Process via Cellular Automata Method. [PDF]

Materials (Basel), 2022
Zhang Y, Zhou W, Tang J, He Y.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Study of Properties of Composite Cementitious Materials with Sulfoaluminate Cement and Solid Waste Based on Compaction Forming Process. [PDF]

Materials (Basel)
Ma Z, Wang X, Yu M, Chen S, Liu J, Li J, Wang J, Sun H, Mao Y, Hu Z, Wang W.   +10 more
europepmc   +1 more source

Minimizing the Main Strains and Thickness Reduction in the Single Point Incremental Forming Process of Polyamide and High-Density Polyethylene Sheets. [PDF]

Materials (Basel), 2023
Rosca N, Oleksik M, Rosca L, Avrigean E, Trzepieciński T, Najm SM, Oleksik V.   +6 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source