Results 21 to 30 of about 11,011 (206)

Formoterol, a β2-adrenoreceptor agonist, induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury

Neurobiology of Disease, 2020
Traumatic brain injury (TBI) leads to acute necrosis at the site of injury followed by a sequence of secondary events lasting from hours to weeks and often years.
Hemendra J. Vekaria, W. Brad Hubbard, Natalie E. Scholpa, Malinda L. Spry, Jennifer L. Gooch, Sydney J. Prince, Rick G. Schnellmann, Patrick G. Sullivan   +7 more
doaj   +1 more source

Fixed-dose combination fluticasone/formoterol for asthma treatment in a real-world setting: meta-analysis of exacerbation rates and asthma control

European Clinical Respiratory Journal, 2023
Background: Treatment guidelines for asthma management are derived almost exclusively from the results of controlled clinical trials undertaken in carefully selected patient populations; meaning that their outcomes may not reflect the true performance of
Alberto Papi, Murtaza Qasuri, Ernestine Chung, Mohamed Abdelbaset, Mohamed Aly Moussa, Vibeke Backer, Olaf Schmidt, Omar Usmani   +7 more
doaj   +1 more source

Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma [PDF]

, 2010
Background Formoterol is a long-acting beta(2)-agonist but because it has a fast onset of action it can also be used as a relief medication. Objectives To asses the efficacy and safety of formoterol as reliever therapy in comparison to short-acting ...
Christopher J Cates, Emma J Welsh, Welsh, EJ, Cates, CJ   +3 more
core   +1 more source

Efficacy and safety of inhaled formoterol 4.5 and 9 μg twice daily in Japanese and European COPD patients: Phase III study results

BMC Pulmonary Medicine, 2011
Background This study evaluated the efficacy and safety of the long-acting β2-agonist formoterol in patients with moderate-to-severe COPD. Methods This double-blind, placebo-controlled, parallel-group, multinational phase III study randomized patients ...
Bogdan Miron A, Aizawa Hisamichi, Fukuchi Yoshinosuke, Mishima Michiaki, Nishimura Masaharu, Ichinose Masakazu   +5 more
doaj   +1 more source

Safety and Effectiveness of As-Needed Formoterol in Asthma Patients Taking Inhaled Corticosteroid (ICS)-Formoterol or ICS-Salmeterol Maintenance Therapy

, 2023
BACKGROUND: As-needed low-dose inhaled corticosteroid (ICS)-formoterol reliever is recommended in patients with asthma prescribed maintenance ICS-formoterol. Clinicians often ask whether ICS-formoterol reliever can be used with other maintenance ICS-long-
Jorup, C, Brusselle, G, Anderson, GP, Lamarca, R, Gustafson, P, Reddel, HK   +5 more
core   +2 more sources

Cost-utility of as-needed ICS-formoterol versus to maintenance ICS in mild to moderate persistent asthma

BMC Pulmonary Medicine, 2021
Background Recent asthma guidelines, such as the Global Initiative for Asthma (GINA), recommend in adult patients as-needed inhaled corticosteroids (ICS)-formoterol as an alternative to maintenance ICS in mild to moderate persistent asthma.
Jefferson Antonio Buendía, Diana Guerrero Patiño   +1 more
doaj   +1 more source

Fluticasone/formoterol combination therapy is as effective as fluticasone/salmeterol in the treatment of asthma, but has a more rapid onset of action: an open-label, randomized study

BMC Pulmonary Medicine, 2011
Background The inhaled corticosteroid (ICS) fluticasone propionate (fluticasone) and the long-acting β2-agonist (LABA) formoterol fumarate (formoterol) are being made available as a combination product (fluticasone/formoterol, flutiform®) in a single ...
McAulay Kirsten, Dymek Andrzej, Bodzenta-Lukaszyk Anna, Mansikka Heikki   +3 more
doaj   +1 more source

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

, 2010
Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Christopher J Cates, Lasserson, TJ, Toby J Lasserson, Cates, CJ   +3 more
core   +1 more source

Effect of beta2-adrenergic agonists on eosinophil adhesion, superoxide anion generation, and degranulation

Allergology International, 2015
Background: Eosinophils play important roles in the development of asthma exacerbation. Viral infection is a major cause of asthma exacerbation, and the expression of IFN-γ-inducible protein of 10 kDa (IP-10) and cysteinyl leukotrienes (cysLTs) is up ...
Toru Noguchi, Kazuyuki Nakagome, Takehito Kobayashi, Yutaka Ueda, Tomoyuki Soma, Hidetomo Nakamoto, Makoto Nagata   +6 more
doaj   +1 more source

Combination formoterol and inhaled steroid versus beta(2)-agonist as relief medication for chronic asthma in adults and children (Review)

, 2009
Background Formoterol has a fast onset of action and can therefore be used to relieve symptoms of asthma. A combination inhaler can deliver formoterol with different doses of inhaled corticosteroid; when used as a reliever both drugs will be delivered ...
Lasserson, TJ, Cates, CJ
core   +1 more source