Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease:a post-hoc analysis of the randomized PINNACLE trials [PDF]
Background: Glycopyrrolate (GP)/formoterol fumarate (FF; GFF) metered dose inhaler is a fixed-dose combination dual bronchodilator for patients with chronic obstructive pulmonary disease (COPD); however, whether the efficacy in patients without current ...
A Anzueto +32 more
core +2 more sources
Contact Dermatitis, Volume 94, Issue 6, Page 717-719, June 2026.
Eglė Janušonytė +3 more
wiley +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
COPD: Optimizing Treatment [PDF]
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila +2 more
core +1 more source
Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
A Hardwell +30 more
core +1 more source
ABSTRACT Acute pulmonary embolism (PE) is a prevalent cardiovascular condition with significant mortality and morbidity. Treatment strategies vary according to risk stratification. While anticoagulation is sufficient for low‐risk patients, high‐risk cases often necessitate systemic thrombolysis (ST) or surgical embolectomy.
Mohammadreza Motazedian +3 more
wiley +1 more source
Anthony D D’Urzo,1 Dave Singh,2 James F Donohue,3 Edward M Kerwin,4 Anna Ribera,5 Eduard Molins,5 Ferran Chuecos,5 Diana Jarreta,5 Esther Garcia Gil5 1Department of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto,
D'Urzo AD +8 more
doaj
Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study [PDF]
Background Aclidinium/formoterol is a twice-daily (BID) fixed-dose combination (FDC) in development for chronic obstructive pulmonary disease (COPD).
Anne Leselbaum +8 more
core +1 more source
Well‐characterized, chemically synthesized molecules related to LGD‐4033 metabolism were used as analytical standards for the analysis of LGD‐4033 post‐administration urine samples. This approach offered further insights into LGD‐4033 metabolism, providing solid experimental proof for the structure of important previously reported metabolites and ...
Yiannis S. Angelis +5 more
wiley +1 more source
Patient-physician discordance in assessment of adherence to inhaled controller medication: a cross-sectional analysis of two cohorts [PDF]
We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance.(SFRH/BPD/115169/2016) funded by Fundação para a Ciência e Tecnologia (FCT); ERDF (European Regional ...
Afonso, Ivete +68 more
core +3 more sources

