Assessment of drug permeability using a small airway microphysiological system
BackgroundThere is a need to reliably predict the permeability of inhaled compounds during the development of new and generic drugs. A small airway microphysiological system (MPS) that can recapitulate the pulmonary air-liquid interface (ALI) with ...
Robert M. Geiger +18 more
doaj +1 more source
Estimating the economic consequences of an increased medication adherence due to a potential improvement in the inhaler technique with Spiromax compared with Turbuhaler in patients with moderate-to-severe chronic obstructive pulmonary disease in Spain [PDF]
The objective of this study was to estimate the economic impact of the introduction of DuoResp® Spiromax®, budesonide/formoterol fixed-dose combination (FDC), focusing on an increase in medication adherence due to an enhancement of the inhalation ...
Bijedic, Adi +6 more
core +1 more source
Expanding Disease Definitions in Guidelines and Expert Panel Ties to Industry:A Cross-sectional Study of Common Conditions in the United States [PDF]
BACKGROUND: Financial ties between health professionals and industry may unduly influence professional judgments and some researchers have suggested that widening disease definitions may be one driver of over-diagnosis, bringing potentially unnecessary ...
Bero, Lisa +5 more
core +4 more sources
Polymorphism of spironolactone: An unprecedented case of monotropy turning to enantiotropy with a huge difference in the melting temperatures [PDF]
Postprint (author's final ...
Barrio Casado, María del +4 more
core +4 more sources
Tashkin DP, Doherty DE, Kerwin E, Matiz-Bueno CE, Knorr B, Shekar T, Banerjee S, Staudinger H. Efficacy and safety of a fixed-dose combination of mometasone furoate and formoterol fumarate in subjects with moderate to very severe COPD: results from a 52 ...
Tashkin DP +7 more
doaj
Sebastien Boisseau,1 Murtaza Qasuri,1 Weng Tong Ho,1 Wrik Ghosh,2 Yacine Hadjiat1 1Mundipharma Singapore Holding Pte Limited, Singapore; 2Costello Medical Singapore Pte Ltd, SingaporeCorrespondence: Yacine HadjiatMundipharma Singapore Holding Pte Limited,
Boisseau S +4 more
doaj
Background Long-acting muscarinic antagonist (LAMA) and long-acting β2-agonist (LABA) bronchodilators are key to the pharmacologic treatment of chronic obstructive pulmonary disease (COPD).
Edward M. Kerwin +4 more
doaj +1 more source
EE602 Budget Impact Analysis of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate for COPD in the Italian Healthcare System [PDF]
Danny Gibson +4 more
openalex +1 more source

