AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Frontiers in Public HealthIntroductionThe Texas Epidemic Public Health Institute (TEPHI) aims to keep Texans healthy and the economy strong by preparing for the next infectious disease outbreak.
Kayla E. Ruch +4 more
doaj +1 more source
Independent External Monitoring Agricultural Report 2014 Syngenta, Romania Galati Corn [PDF]
, 2014 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Towards the future of personalized medicine: digital twin technology [PDF]
Exploration of Digital Health TechnologiesDigital twin technology is emerging as a transformative paradigm in healthcare, shifting practice from provider-centered models toward more personalized forms of medicine.
Keren Mazuz, Seema Biswas
doaj +1 more source
Acetaminophen forms toxics during chlorination | News Briefs: Controlling allergens improves asthma ` Making H2O2 greener ` Record renewable growth ` ... and renewable power purchases are rising | Engineered wetlands may pose risks to wildlife | Lead a hazard in post-Katrina sludge | Household cleaners can remove lead dust | EPA updates air-quality model [PDF]
Environmental Science & Technology, 2006 Anke Schaefer +3 more
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
BIM-GIS-Based Approach for Quality Management Aligned with ISO 9001
Applied SciencesQuality management during construction is critical to ensuring compliance with technical specifications and quality standards. Traditional practices often rely on manual, paper-based documentation, leading to inefficiencies, data fragmentation, and poor ...
Pablo Araya-Santelices +4 more
doaj +1 more source
Tuberculosis in hospital environment: clinical profile in a tertiary hospital from Ceará and level of knowledge of health personnel about control measures [PDF]
Revista Brasileira em Promoção da Saúde, 2010 Objectives: To describe clinical and epidemiological characteristics of inpatients with tuberculosis (TB) and to assess the knowledge of health personnel on fundamental concepts about TB and control measures for pulmonary tuberculosis in a hospital ...
Roberto da Justa Pires Neto +7 more
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