Results 71 to 80 of about 240,463 (265)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Cybrarians Journal, 2009 Libraries and the information services they provide on the Internet face a set of challenges imposed by rapid developments in information technology and remote communications.
Mohamed Helmy
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
AACR2 and catalogue production technology: The relevance of cataloguing principles to the online environment [PDF]
, 1997 More than thirty five years have passed since the Paris Conference and cataloguers have witnessed profound changes in many aspects of catalogue production technology and also in bibliographic control and access during this period of time.
Fattahi, Rahmatollah
core +1 more source
Integrity of Medicare customer data [PDF]
, 2014 This audit examined the effectiveness of the Department of Human Services’ management of Medicare customer data and the integrity of this data. Audit objective, criteria and scope The objective of the audit was to examine the effectiveness of the ...
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
康复学报, 2022 Since 2016, Peking University Third hospital has been entrusted by the National Health Commission to undertake the work of National Center for Healthcare Quality Management in Rehabilitation Medicine.
ZHOU Mouwang
doaj
TREATMENT OF EPILEPSY IN PATIENTS OF “VU LNERABLE” AGE: THE ADOLESCENTS AND THE ELDERLY
Эпилепсия и пароксизмальные состояния, 2017 The incidence of epilepsy is highest in children and in elderly people (over 60 years of age). In about 75% of cases, the first seizures occur before the age of 16 with the maximal occurrence observed before the age of 10 [1].
K. V. Voronkova +3 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source