Results 81 to 90 of about 1,446,439 (274)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
HIGH DEFINITION ECG: FROM PRESENT TO FUTURE
Российский кардиологический журнал, 2010 The study was aimed at assessing qualitative characteristics of late ventricular potentials (LVP) in 104 patients with various clinical forms of coronary heart disease (CHD).
I. A. Latfullin +3 more
doaj
Discover Public HealthIntroduction Non-communicable diseases (NCDs) are responsible for 74% of global deaths annually, with significant issues including cardiovascular diseases, diabetes, stroke, and cancer. In India, the prevalence of hypertension is 74.7%, but only 12% have
Kahan S. Mehta +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Standardizing Corneal Transplantation Records Using openEHR: Case Study
JMIR Medical InformaticsBackgroundCorneal transplantation, also known as keratoplasty, is a widely performed surgical procedure that aims to restore vision in patients with corneal damage. The success of corneal transplantation relies on the accurate and
Diana Ferreira +5 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Circular 03/12 : audit of the use of funds : adult and community learning, former external institutions and sixth form funding in local education authorities for 2002/03 [PDF]
, 2003 "This circular provides guidance to local education authorities (LEAs) on the preparation of Use of Funds statements for their adult and community learning (ACL) and former external institutions (EI) funding allocations (2002/03).
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source