Results 201 to 210 of about 2,429,415 (389)
Advanced Science, EarlyView.This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma +10 more
wiley +1 more source
Evaluation of Formulated Inert Larval Diets for Giant Freshwater Prawn, Macrobrachium rosenbergii Weaning From Artemia [PDF]
, 2008 Shivananda Murthy +4 more
openalex +1 more source
Advanced Science, EarlyView.Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang +10 more
wiley +1 more source
Increasing levels of phytase in diets formulated with reduced available phosphorus content supplied to male and female broilers [PDF]
, 2014 Luciana de Paula Naves +7 more
openalex +1 more source
Advanced Science, EarlyView.This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye +18 more
wiley +1 more source
Formulated Diets Drive Gonadal Maturity but Reduce Larval Success in Paracentrotus lividus [PDF]
Bruno Pinto +9 more
openalex +1 more source
Nanozymes Integrated Biochips Toward Smart Detection System
Advanced Science, EarlyView.This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
An Optimization Tool to Formulate Diets within a Supplementary Nutrition Program for Children [PDF]
Fathima Ayoob +19 more
openalex +1 more source
Advanced Science, EarlyView.Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin +10 more
wiley +1 more source