Results 281 to 290 of about 2,429,415 (389)

Building a humane scientific future: Second Asia Laboratory Animal Day

Animal Models and Experimental Medicine, EarlyView.
Frontiers in Laboratory Animal Handling and Experimental Design: Bridging Ethics and Excellence Theme: Good Science with Good Care Ethical Framework: CCSEA & IAEC oversight | 3Rs (Replacement, Reduction, Refinement) | Transparent documentation Animal Handling & Anatomy: Mice • Rats • Rabbits • Guinea pigs Gentle restraint • Anatomical landmarks ...
Vijay Pal Singh, Himalaya Bhardwaj, R. K. Shakthi Devan, Rahul Thorat   +3 more
wiley   +1 more source

Simvastatin Improves the High-Fat-Diet-Induced Metabolic Disorder in Juvenile Chinese Giant Salamander (<i>Andrias davidianus</i>) Through Inhibiting Endoplasmic Reticulum Stress and Enhancing Mitochondrial Function. [PDF]

Animals (Basel)
Wang Y, Chen J, Dong Y, Du J, Ma S, Wang H, Wang Y, Li X.   +7 more
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Effects of dietary vitamin E on growth, immune response, antioxidant capacity, intestinal histomorphology, digestibility and disease resistance of juvenile Pacific white shrimp (Penaeus vannamei). [PDF]

PLoS One
Ko D, Medagoda N, Shin J, Hasanthi M, Bae J, Min BH, Lee KJ.   +6 more
europepmc   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Diet-induced steatohepatitis does not cause heart failure with preserved ejection fraction in male middle-aged C57BL/6N mice. [PDF]

PLoS One
Kessinger CW, Chen L, Huang F, Lin J, Davenport A, Lin Z.   +5 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Micronized Dispersible Ferric Pyrophosphate (MDFP) in Extruded Rice Desserts: High Iron Bioavailability and Good Sensory Acceptance by Children. [PDF]

J Food Sci
Ferreira DCM, de Oliveira TV, Moreira MEC, Pirozi MR, Martino HSD, de Oliveira EB.   +5 more
europepmc   +1 more source

Brazil Nut Flour as a Functional Ingredient: Effects on Texture, Composition and Sensory Profile of Reduced‐Sugar Gluten‐Free Cookies

Journal of the American Oil Chemists' Society, EarlyView.
Graphical abstract of the characterization of Brazil nut flour (BNF) and the impact of its addition on the nutritional and sensory properties of gluten‐free and low‐sugar cookies. The results show that BNF contributed to an improved nutritional quality of the cookies and enhanced overall product acceptance.
Ana Luísa Schiessl Fabri, Lucas Lourenço dos Santos, Giustino Tribuzi, Pedro Luiz Manique Barrreto, Renata Dias de Mello Castanho Amboni, Maria Manuela Camino Feltes   +5 more
wiley   +1 more source

Modulating One-Carbon Metabolism with B-Vitamins to Protect the Retinal Barrier and Prevent Retinal Degeneration. [PDF]

Nutrients
Abouhish H, Shalaby L, Elzayat O, Peddireddy N, Tawfik A.   +4 more
europepmc   +1 more source