Results 31 to 40 of about 1,383,313 (217)

Case report: Novel phenotype in central 22q11.2 deletion syndrome

Clinical Case Reports, 2020
Deletions within 22q11.2 are one of the most common microdeletions studied. We report a case of central 22q11.2 deletion with abnormal dentition, a feature not previously described in this condition.
Patrick Dideum, Luis Rohena, Janet Berg, Candace Percival   +3 more
doaj   +1 more source

Oxidized Zirconium Total Knee Arthroplasty Implant Failure in a Patient With Knee Instability

Arthroplasty Today, 2020
Oxidized zirconium was introduced as an alternative bearing surface to decrease polyethylene wear and reduce aseptic mechanical failure of hip and knee arthroplasties.
Lydia Kore, MD, Taylor Bates, MD, Gavin Mills, MD, Dustin Lybeck, MD   +3 more
doaj   +1 more source

ASCs derived from burn patients are more prone to increased oxidative metabolism and reactive oxygen species upon passaging

Stem Cell Research & Therapy, 2021
Background Patients with severe burn injury (over 20% of the total body surface area) experience profound hypermetabolism which significantly prolongs wound healing.
David M. Burmeister, Grace Chu-Yuan Chu, Tony Chao, Tiffany C. Heard, Belinda I. Gómez, Linda E. Sousse, Shanmugasundaram Natesan, Robert J. Christy   +7 more
doaj   +1 more source

HMGB1 Inhibition to Ameliorate Organ Failure and Increase Survival in Trauma

Biomolecules, 2022
Several preclinical and clinical reports have demonstrated that levels of circulating high mobility group box 1 protein (HMGB1) are increased early after trauma and are associated with systemic inflammation and clinical outcomes.
Zhangsheng Yang, Milomir O. Simovic, Peter R. Edsall, Bin Liu, Tomas S. Cancio, Andriy I. Batchinsky, Leopoldo C. Cancio, Yansong Li   +7 more
doaj   +1 more source

Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

Critical Care, 2017
Background Restoration of endothelial glycocalyx (EG) barrier may be an essential therapeutic target for successful resuscitation. The aim of this study was to compare in vivo the effects of resuscitation with normal saline (NS) to lactated Ringer’s ...
Luciana N. Torres, Kevin K. Chung, Christi L. Salgado, Michael A. Dubick, Ivo P. Torres Filho   +4 more
doaj   +1 more source

Changes in the excitability of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields

Scientific Reports, 2022
Exposures to radiofrequency electromagnetic fields (RF-EMFs, 100 kHz to 6 GHz) have been associated with both positive and negative effects on cognitive behavior. To elucidate the mechanism of RF-EMF interaction, a few studies have examined its impact on
Ibtissam Echchgadda, Jody C. Cantu, Gleb P. Tolstykh, Joseph W. Butterworth, Jason A. Payne, Bennett L. Ibey   +5 more
doaj   +1 more source

Effects of hemodilution on coagulation function during prolonged hypotensive resuscitation in a porcine model of severe hemorrhagic shock

Trauma Surgery & Acute Care Open, 2023
Background Although hemorrhage remains the leading cause of survivable death in casualties, modern conflicts are becoming more austere limiting available resources to include resuscitation products.
Clifford G Morgan, Leslie E Neidert, Emily N Hathaway, Sylvain Cardin, Jacob J Glaser, Peter J Hemond, Michael M Tiller   +6 more
doaj   +1 more source

Development of a Modular Tissue Phantom for Evaluating Vascular Access Devices

Bioengineering, 2022
Central vascular access (CVA) may be critical for trauma care and stabilizing the casualty. However, it requires skilled personnel, often unavailable during remote medical situations and combat casualty care scenarios.
Emily N. Boice, David Berard, Jose M. Gonzalez, Sofia I. Hernandez Torres, Zechariah J. Knowlton, Guy Avital, Eric J. Snider   +6 more
doaj   +1 more source

The Development and Usability Assessment of an Augmented Reality Decision Support System to Address Burn Patient Management

BioMedInformatics
Critical care injuries, such as burn trauma, require specialized skillsets and knowledge. A clinical decision support system to aid clinicians in providing burn patient management can increase proficiency and provide knowledge content for specific ...
Sena Veazey, Nicole Caldwell, David Luellen, Angela Samosorn, Allison McGlasson, Patricia Colston, Craig Fenrich, Jose Salinas, Jared Mike, Jacob Rivera, Maria Serio-Melvin   +10 more
doaj   +1 more source

An Automated Hardware-in-Loop Testbed for Evaluating Hemorrhagic Shock Resuscitation Controllers

Bioengineering, 2022
Hemorrhage remains a leading cause of death, with early goal-directed fluid resuscitation being a pillar of mortality prevention. While closed-loop resuscitation can potentially benefit this effort, development of these systems is resource-intensive ...
Eric. J. Snider, David Berard, Saul J. Vega, Sofia I. Hernandez Torres, Guy Avital, Emily N. Boice   +5 more
doaj   +1 more source