Results 31 to 40 of about 60,015 (288)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Japan’s construction of defensive fortifications and its implications for East Asian relations during the Tang dynasty

open access: yesHumanities & Social Sciences Communications
Japan’s construction of fortifications throughout its history has been a subject of scholarly interest. Japan has been building fortifications for generations, from Muzuki and stone fortifications at home to Japanese fortifications on the Korean ...
Zhuang Li, Kehua Liu
doaj   +1 more source

Medieval Layer of Ardinskoe Hillfort (based on study materials of 2013)

open access: yesПоволжская археология, 2018
The paper features materials obtained as a result of studying Ardinskoe hillfort in 2013. It provides characteristics of the defensive structures and the rampart structure, and analyses the ceramic complex and material items.
Mikheev Alexey V.
doaj   +1 more source

Roadmap to Precision 3D Printing of Cellulose: Rheology‐Guided Formulation, Fidelity Assessment, and Application Horizons

open access: yesAdvanced Materials Technologies, EarlyView.
This critical review presents a comprehensive roadmap for the precision 3D printing of cellulose. Quantitative correlations link ink formulation and rheological properties to print fidelity and final material performance. This framework guides the development of advanced functional materials, from biomedical scaffolds to electromagnetic shielding ...
Majed Amini   +3 more
wiley   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

open access: yesAdvanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz   +20 more
wiley   +1 more source

Chronique des recherches sur le Mont Beuvray : 2006-2008

open access: yesRevue Archéologique de l’Est, 2010
This paper assesses the main research carried out at the Mount Beuvray and its surroundings between 2006 and 2008 pertaining to the International Research programme of the Bibracte oppidum. At the programme’s completion, several excavations have provided
Fabrice Bessière, Vincent Guichard
doaj   +1 more source

“Disguised in scarlet”. Hume and Turin in 17481 [PDF]

open access: yes, 2010
Archive Research concerning the following subjects: Hume in Turin (8 May - 29 November 1748) as secretary and aide-de-camp to General St Clair. St Clair's mission and correspondence (his letters written by Hume).
Mazza, Emilio, Piccoli, Edoardo
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Conservation and Use of Archaeological Heritage in Ulyanovsk Oblast

open access: yesПоволжская археология, 2017
This article addresses the problems of preservation and use of archaeological sites on the territory of the Ulyanovsk Oblast, where over 700 sites were discovered.
Semykin Yuriy A
doaj   +1 more source

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