Results 101 to 110 of about 264,379 (313)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Global sensitivity of EEG source analysis to tissue conductivity uncertainties

Frontiers in Human Neuroscience
IntroductionTo reliably solve the EEG inverse problem, accurate EEG forward solutions based on a detailed, individual volume conductor model of the head are essential.
Johannes Vorwerk, Carsten H. Wolters, Carsten H. Wolters, Daniel Baumgarten   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Forward Modeling of Galaxy Populations for Cosmological Redshift Distribution Inference [PDF]

, 2023
We present a forward-modeling framework for estimating galaxy redshift distributions from photometric surveys. Our forward model is composed of: a detailed population model describing the intrinsic distribution of the physical characteristics of galaxies,
Leja, Joel, Mortlock, Daniel, Leistedt, Boris, Peiris, Hiranya, Alsing, Justin   +4 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Three-Dimensional Marine Magnetotelluric Parallel Forward Modeling in Conductive and Magnetic Anisotropic Medium Using Finite-Element Method Based on Secondary Field

Journal of Marine Science and Engineering
The marine magnetotelluric (MMT) method is a significant tool extensively utilized in offshore studies, including the understanding of the Earth’s tectonics and hydrocarbon exploration.
Zongyi Zhou, Tiaojie Xiao, Junjun Zhou, Xiaoxiong Zhu, Bo Yang, Chunye Gong, Jie Liu, Yun Wang   +7 more
doaj   +1 more source

CutFEM forward modeling for EEG source analysis. [PDF]

Front Hum Neurosci, 2023
Erdbrügger T, Westhoff A, Höltershinken M, Radecke JO, Buschermöhle Y, Buyx A, Wallois F, Pursiainen S, Gross J, Lencer R, Engwer C, Wolters C.   +11 more
europepmc   +1 more source

Long Memory and Structural Changes in the Forward Discount: An Empirical Investigation [PDF]

Many empirical studies find a negative correlation between the returns on the nominal spot exchange rate and the lagged forward discount. This forward discount anomaly implies that the current forward rate is a biased predictor of the future spot rate. A
Eric Zivot, Kyongwook Choi
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Modeling long-term electricity forward prices

In contrast to forwards and futures on storable commodities, prices of long-term electricity forwards exhibit a dynamics different to that of short-term and mid-term prices.
Povh, Martin, Fleten, Stein-Erik
core