Results 91 to 100 of about 1,333,112 (303)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe radio imaging method (RIM) can be used in underground mines to identify geologically hazardous areas; however, it does not yield accurate results. To address this issue, a high-frequency (1–8 MHz) RIM is proposed here for the fine detection of
Shun Yang +3 more
doaj +1 more source
Modeling the Currency Forward Risk Premium: Theory and Evidence [PDF]
There is a huge literature on the existence of risk premia in the foreign exchange markets and its influence in explaining the divergence between the forward exchange rate and the subsequently realised spot exchange rate.
Carl Chiarella, Ram Bhar, Toan Pham
core
A modified inverse scheme for magnetic material characterization of an electromagnetic device with minimal influence of multiple geometrical uncertainties [PDF]
, 2012 The properties of the magnetic core materials inside electromagnetic devices can be retrieved by solving an electromagnetic inverse problem. In such inverse problems, the unknown parameters are recovered by interpreting well-chosen measurements using a ...
Dupré, Luc +1 more
core
Functional Methods in Stochastic Systems
, 2012 Field-theoretic construction of functional representations of solutions of stochastic differential equations and master equations is reviewed. A generic expression for the generating function of Green functions of stochastic systems is put forward ...
A.N. Vasiliev +9 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Global-Scale Numerical Modeling of Seismic Wave Propagation Using PREM and Unstructured Triangular Meshing: Insights into the Layered Structure of Earth [PDF]
مجله فیزیک زمین و فضاThe Preliminary Reference Earth Model (PREM) provides a robust framework for understanding seismic wave propagation through Earth’s layered interior. This study employs numerical forward modeling to simulate P-wave and S-wave ray paths, travel times, and
Amir Yazdanpanah, Maysam Abedi
doaj +1 more source
The parameters and measurements of the destabilizing actions of rotating machines, and the assumptions of the 1950's [PDF]
The measurability of destabilizing actions is demonstrated for a rotor built to produce a forward circular, self excited malfunction (gas whip). It is argued that the continued use of past modeling technqiues is unfortunate in that it has led to the use ...
Bently, D. E.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source