Results 71 to 80 of about 1,333,112 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A cubed-sphere based method for global and regional modeling of the lithospheric magnetic field

open access: yesEarth and Planetary Physics
The Earth’s magnetic field, which has been extensively observed from ground to satellite altitudes over several decades, originates from multiple sources, such as the core dynamo, the conductive mantle, the magnetized lithosphere, and the space current ...
Liang Yin   +5 more
doaj   +1 more source

Moving Forward: On the Limits of Motor-Based Forward Models

open access: yesTrends in Cognitive Sciences, 2019
The human ability to anticipate the consequences that result from action is an essential building block for cognitive, emotional, and social functioning. A dominant view is that this faculty is based on motor predictions, in which a forward model uses a copy of the motor command to predict imminent sensory action-consequences. Although this account was
Dogge, Myrthel   +2 more
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Fictitious Point Technique Based on Finite-Difference Method for 2.5D Direct-Current Resistivity Forward Problem

open access: yesMathematics
With the widespread application of the direct-current resistivity method, searching for accurate and fast-forward algorithms has become the focus of research for geophysicists and engineers.
Xiaozhong Tong, Ya Sun
doaj   +1 more source

Forward models and passive psychotic symptoms [PDF]

open access: yesFrontiers in Human Neuroscience, 2015
Pickering and Clark (2014) present two ways of viewing the role of forward models in human cognition: the auxiliary forward model (AFM) account and the integral forward model (IFM) account. The AFM account “assumes a dedicated prediction mechanism implemented by additional circuitry distinct from the core mechanisms of perception and action” (p.
openaire   +4 more sources

Modeling long-term electricity forward prices [PDF]

open access: yes
In contrast to forwards and futures on storable commodities, prices of long-term electricity forwards exhibit a dynamics different to that of short-term and mid-term prices.
Fleten, Stein-Erik, Povh, Martin
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Three-Dimensional Magnetotelluric Forward Modeling Using Multi-Task Deep Learning with Branch Point Selection

open access: yesRemote Sensing
Magnetotelluric (MT) forward modeling is a key technique in magnetotelluric sounding, and deep learning has been widely applied to MT forward modeling.
Fei Deng   +3 more
doaj   +1 more source

The Analysis of Forward-Looking Monetary Policy in a SVAR Framework [PDF]

open access: yes
This paper analyzes forward-looking monetary policy rules in structural VAR’s. First, an approach for modeling a monetary policy which aims at a strict medium term inflation or output growth target is developed.
Carlos Lenz   +3 more
core  

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