Results 31 to 40 of about 2,210,716 (290)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Change in SiC MOSFET body-diode voltage drop in TO-247 packages during inverse-mode and forward-mode power cycling test

, 2022
Body-diode voltage drop has been identified as a reliable parameter for both as a temperature-sensitive electrical parameter (TSEP) to estimate the SiC MOSFET junction temperature and as a failure precursor to identify any package related degradation ...
Norrga, Staffan,, Farjah, Amin,, Singh, B. P.,, Nee, Hans-Peter,, Chaudhury, K. R.,   +4 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Applications, Prospects and Challenges of Silicon Carbide Junction Field Effect Transistor (SIC JFET)

International Journal of Advances in Telecommunications, Electrotechnics, Signals and Systems, 2016
Properties of Silicon Carbide Junction Field Effect Transistor (SiC JFET) such as high switching speed, low forward voltage drop and high temperature operation have attracted the interest of power electronic researchers and technologists, who for many ...
Frederick Ojiemhende Ehiagwina, Olufemi Oluseye Kehinde, Lateef Olashile Afolabi, Hassan Jimoh Onawola, Nurudeen Ajibola Iromini   +4 more
doaj   +1 more source

Fast-Switching-Speed, Low-Forward-Voltage-Drop Static Induction(SI) Thyristor.

IEEJ Transactions on Industry Applications, 1995
An SI thyristor using a normally-off planar-gate structure in a low power class has been developed for the use as a power switching device in a three-phase inverter circuit. A 600V-15A class SI thyristor with very fast switching time (tgt, tgq) and low forward voltage drop (VTM) was designed and fabricated.
Maeda, Mitsuhide, Keno, Takuji, Suzuki, Yuji, Abe, Toshiro   +3 more
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Online Calibration Method for High-Precision On-State Voltage Measurement of Power Semiconductors

IEEE Access
This paper presents an online high-precision calibration method for on-state voltage measurement of power semiconductors using active temperature control.
Karla Drazenovic, Luka Matic, Viktor Sunde, Zeljko Ban   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Experimental Study on a Passive Fuel Cell/Battery Hybrid Power System

Energies, 2013
A laboratory-scale passive hybrid power system for transportation applications is constructed and tested in this study. The hybrid power system consists of a fuel cell stack connected with a diode, a lithium-ion battery pack connected with a DC/DC power ...
Yong-Song Chen, Sheng-Miao Lin, Boe-Shong Hong   +2 more
doaj   +1 more source

Analysis of Drop Out and Load Current for on Chip Voltage Regulators [PDF]

, 2018
LDO (Low Drop-Out) Voltage regulators are commonly used in electronics power supply circuit. DC linear voltage regulator is a LDO regulator that can regulate the output voltage even when the power supply voltage is very near to the output voltage.
Dr S. K Bishnoi, Vijendra K Maurya, Mohammad sabir
core