Results 31 to 40 of about 43,658 (259)

Sleep Deprivation in the Forward-Forward Algorithm

open access: yesCoRR, 2023
This paper aims to explore the separation of the two forward passes in the Forward-Forward algorithm from a biological perspective in the context of sleep. We show the size of the gap between the sleep and awake phase influences the learning capabilities of the algorithm and highlight the importance of negative data in diminishing the devastating ...
Mircea Tudor Lica, David Dinucu-Jianu
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

La auditoría de los instrumentos financieros derivados

open access: yesRevista de Ciencias Economicas, 2010
El tema de los derivados ha tomado gran relevancia en Costa Rica durante los últimos años, principalmente como consecuencia de la adopción del sistema de bandas para definir el tipo de cambio. Por tratarse de un producto nuevo y de mayor sofisticación es
Vernor Mesén Figueroa
doaj  

Looking Forwards and Looking Back

open access: yesEvidence Based Library and Information Practice, 2012
No abstract.
Alison Brettle
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On Advancements of the Forward-Forward Algorithm [PDF]

open access: yes2025 11th International Conference on Control, Decision and Information Technologies (CoDIT)
The Forward-Forward algorithm has evolved in machine learning research, tackling more complex tasks that mimic real-life applications. In the last years, it has been improved by several techniques to perform better than its original version, handling a challenging dataset like CIFAR10 without losing its flexibility and low memory usage.
Ortiz Torres, Mauricio   +2 more
openaire   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hydration management in rugby: a comparative study on the forward and back positions of the Indonesian national team

open access: yesPedagogy of Physical Culture and Sports
Background and Study Aim. In the Indonesian national rugby team, there is a lack of awareness among back and forward players about the amount of fluids they lose while playing their respective positions.
Fatah Nurdin   +5 more
doaj   +1 more source

Forward–forward training of an optical neural network

open access: yesOptics Letters, 2023
Neural networks (NNs) have demonstrated remarkable capabilities in various tasks, but their computation-intensive nature demands faster and more energy-efficient hardware implementations. Optics-based platforms, using technologies such as silicon photonics and spatial light modulators, offer promising avenues for achieving this goal.
Ilker Oguz   +8 more
openaire   +3 more sources

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