Results 101 to 110 of about 26,336 (149)

Clinical Trial: The Effects of Emulsifiers in the Food Supply on Disease Activity in Crohn's Disease: An Exploratory Double‐Blinded Randomised Feeding Trial

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1276-1289, April 2025.
Diets modelled on healthy eating guidelines, but differing in the content of emulsifiers available in the food supply, improved disease activity on sonographic criteria, Harvey‐Bradshaw Index and patient‐reported outcomes over 4 weeks in 24 patients with active Crohn's disease, with no differences according to the content of emulsifiers.
Jessica A. Fitzpatrick, Peter R. Gibson, Kirstin M. Taylor, Ellen J. Anderson, Antony B. Friedman, Zaid S. Ardalan, Rebecca L. Smith, Emma P. Halmos   +7 more
wiley   +1 more source

Candidate Key Proteins in Tinnitus-A Bioinformatic Study of Synaptic Transmission in the Inferior Colliculus. [PDF]

Int J Mol Sci
Gross J, Knipper M, Mazurek B.
europepmc   +1 more source

Robust CAR T‐cell expansion and superior outcomes in DLBCL patients in complete response at infusion

British Journal of Haematology, EarlyView.
In this study, CAR T‐cell expansion and persistence were found to be comparable between CR and non‐CR groups, regardless of the co‐stimulatory domain (CD28 or 4‐1BB) or product used. Furthermore, peripheral blood kinetics—including absolute counts and proportions of total, CD4+ and CD8+ CAR T cells—showed no significant differences between the two ...
Ryo Hanajiri, Hiroya Wakabayashi, Kohei Ishigiwa, Fumiya Ohara, Shiho Hirano, Hirofumi Yokota, Shihomi Kuwano, Katsuya Furukawa, Kazuyuki Shimada, Takahiko Sato, Seitaro Terakura, Hitoshi Kiyoi   +11 more
wiley   +1 more source

Magnetic Fields Influence Visual Responses in Mice

Semo M, Hughes S, Smyllie NJ, Patton AP, Pothecary CA, Tam SE, Buckland J, Brown LA, Reardon PK, Bannerman DM, Hankins MW, Hastings MH, Peirson SN.   +12 more
europepmc   +1 more source

Distinct Impact of Inflammatory Versus Psychophysiological Stress on Brain-Wide Activation of Melanocortin Receptor 4-Expressing Neurons. [PDF]

FASEB J
Cheon M, Kim W, Chung C.
europepmc   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, EarlyView.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source

Comprehensive systems biology analysis of microRNA-101-3p regulatory network identifies crucial genes and pathways in hepatocellular carcinoma. [PDF]

J Genet Eng Biotechnol
Rahimi-Farsi N, Ghorbani A, Mottaghi-Dastjerdi N, Shahbazi T, Bostanian F, Mohseni P, Yazdani F.   +6 more
europepmc   +1 more source

Identification of a Distal Enhancer That Regulates TGF‐β–Induced SNAI1 Expression

Cancer Science, EarlyView.
In TGF‐β–stimulated cells, the activated Smad complex composed of Smad3 and Smad4 associates with the distal super enhancer region 2 (DSE2) and enhances its interaction with the SNAI1 proximal promoter, thus inducing SNAI1 expression. RREB1 regulates the basal activity of the enhancer but not its inducibility by TGF‐β.
Hao Fu, Yuka Itoh, Tomoe Sawaguchi, Shigeo Otake, Chiho Omata, Masao Saitoh, Keiji Miyazawa   +6 more
wiley   +1 more source

Neural and Behavioral Correlates of Individual Variability in Rat Helping Behavior: A Role for Social Affiliation and Oxytocin Receptors. [PDF]

J Neurosci
Hazani R, Breton JM, Trachtenberg E, Ruzal K, Shvalbo B, Kantor B, Maman A, Bigelman E, Cole S, Weller A, Ben-Ami Bartal I.   +10 more
europepmc   +1 more source

CXCL10 Promotes Spinal Macrophage Recruitment via the JAK/STAT3 Pathway to Induce Pain in Experimental Autoimmune Prostatitis

Cell Proliferation, Volume 58, Issue 4, April 2025.
The CXCL10/CXCR3 axis was involved in spinal macrophage infiltration through activating the JAK/STAT3 pathway. The prostate NGF/TrKA axis was involved in the neuroinflammation and pain in chronic prostatitis, and inhibition of NGF could attenuate pain response in chronic prostatitis, which provided novel therapeutic targets for pain treatment in ...
Lei Chen, Ziqi Chen, Jia Chen, Hexi Du, Xianguo Chen, Jing Chen, Hui Wang, Chaozhao Liang   +7 more
wiley   +1 more source