Circulating Fetuin‐A concentrations in rheumatic diseases: a systematic review and meta‐analysis
In this systematic review with meta‐analysis, we identified 19 eligible studies to determine whether there is any change in Fetuin‐A (FtA) concentrations in patients with rheumatic diseases. We observed a significant decrease in FtA concentrations in RD patients (standardized mean difference, SMD = −.91; 95% CI −1.43 to −.39, p = .001).
Biagio Di Lorenzo+6 more
wiley +1 more source
Whole-brain mapping in adult zebrafish and identification of the functional brain network underlying the novel tank test. [PDF]
Rajput N+6 more
europepmc +1 more source
Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya+4 more
wiley +1 more source
Rhusflavone Modulates Osteoclastogenesis Through RANKL-Induced AKT Signaling in Bone Marrow-Derived Macrophages. [PDF]
Yun HM, Kim B, Kim E, Park KR.
europepmc +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva+14 more
wiley +1 more source
Electrical Stimulation of the M1 Activates Somatostatin Interneurons in the S1: Potential Mechanisms Underlying Pain Suppression. [PDF]
Park J, Kim YG, Kim T, Baek M.
europepmc +1 more source
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon+7 more
wiley +1 more source
Single-Cell Transcriptomic Profiling Reveals Regional Differences in the Prefrontal and Entorhinal Cortex of Alzheimer's Disease Brain. [PDF]
Niu RZ, Feng WQ, Chen L, Bao TH.
europepmc +1 more source
Status epilepticus in older adults: A critical review
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward+5 more
wiley +1 more source
Effect of fructo-oligosaccharides on growth performance and meat quality in broilers. [PDF]
Yan Z+9 more
europepmc +1 more source