Results 61 to 70 of about 26,336 (149)

Expanding the Allelic and Clinical Heterogeneity of Movement Disorders Linked to Defects of Mitochondrial Adenosine Triphosphate Synthase

Movement Disorders, EarlyView.
Abstract Background Defects of mitochondrial ATP synthase (ATPase) represent an emerging, yet incompletely understood group of neurodevelopmental diseases with abnormal movements. Objective The aim of this study was to redefine the phenotypic and mutational spectrum of movement disorders linked to the ATPase subunit‐encoding genes ATP5F1A and ATP5F1B ...
Philip Harrer, Magdalena Krygier, Martin Krenn, Volker Kittke, Martin Danis, Georgi Krastev, Alice Saparov, Virginie Pichon, Marlène Malbos, Clarisse Scherer, Ivana Dzinovic, Matej Skorvanek, Robert Kopajtich, Holger Prokisch, Sara Silvaieh, Anna Grisold, Maria Mazurkiewicz‐Bełdzińska, Jean‐Madeleine de Sainte Agathe, Juliane Winkelmann, Jan Necpal, Robert Jech, Michael Zech   +21 more
wiley   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

Molecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti, Martina Giuseffi, Eugenia Giglio, Graziella Marino, Marisabel Mecca   +4 more
wiley   +1 more source

Distortion‐free steady‐state diffusion‐weighted imaging with magnetic resonance fingerprinting

Medical Physics, EarlyView.
Abstract Background Magnetic resonance fingerprinting (MRF) could provide joint T1, T2, and proton density mapping. Measuring diffusion encoding using the MRF framework is promising, given its capacity to generate self‐aligned quantitative maps and contrast‐weighted images from a single scan.
Yiang Wang, Yingying Lin, Di Cui, Edward S. K. Hui, Elaine Y. P. Lee, Peng Cao   +5 more
wiley   +1 more source

Accelerated multi‐shell diffusion MRI with Gaussian process estimated reconstruction of multi‐band imaging

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose This work aims to propose a robust reconstruction method exploiting shared information across shells to increase the acquisition speed of multi‐shell diffusion‐weighted MRI (dMRI), enabling rapid tissue microstructure mapping. Theory and Methods Local q‐space points share similar information.
Xinyu Ye, Karla L. Miller, Wenchuan Wu
wiley   +1 more source

Construction of a Fluorescence‐Based Logic Gate Seeing the Effect of Perchlorate Ions on Hemicyanine Dye–β‐Cyclodextrin Complexes to Certify Safe Drinking Water

ChemistryOpen, EarlyView.
A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M., Shalini Dyagala, Sairathna Choppella, Mahesh Kumar Ravva, Subit Kumar Saha   +4 more
wiley   +1 more source

Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization

The Journal of Pathology, EarlyView.
Abstract Mucinous cystic neoplasms (MCNs) of the pancreas are macroscopic precursors of pancreatic cancer. A similar cystic lesion but lacking the ovarian‐type subepithelial stroma has been recently defined as a simple mucinous cyst (SMC); however, its nature remains unclear. This study aims to define the clinicopathological and molecular profiles of a
Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Andrea Mafficini, Stela Golovco, Michele Simbolo, Serena Pedron, Concetta Sciammarella, Paola Mattiolo, Aldo Mombello, Manuela Villanova, Carlotta Franzina, Francesca Masetto, Calogero Ciulla, Nicola Sperandio, Kohei Fujikura, Masha S. Ahadi, Jaswinder S. Samra, Amber L. Johns, Joanne Verheij, Martijn W.J. Stommel, Hjalmar van Santvoort, Leonor Schubert Santana, Giuseppe Malleo, Michele Milella, Lodewijk A. A. Brosens, Laura D. Wood, David K. Chang, Riccardo De Robertis, Mirko D'Onofrio, Anthony J. Gill, Roberto Salvia, Vincenzo Corbo, Rita T. Lawlor, Aldo Scarpa, Claudio Luchini   +37 more
wiley   +1 more source

Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal‐Sensing Sensor Histidine Kinase ZraS

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra, Pranjal Mahanta, Shubhant Pandey, Rudresh Acharya   +3 more
wiley   +1 more source

Binding Differences of the Peptide‐Substrate–Binding Domain of Collagen Prolyl 4‐Hydroxylases I and II for Proline‐ and Hydroxyproline‐Rich Peptides

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Collagen prolyl 4‐hydroxylase (C‐P4H) catalyzes the 4‐hydroxylation of Y‐prolines of the XYG‐repeat of procollagen. C‐P4Hs are tetrameric α2β2 enzymes. The α‐subunit provides the N‐terminal dimerization domain, the middle peptide‐substrate–binding (PSB) domain, and the C‐terminal catalytic (CAT) domain.
M. Mubinur Rahman, Ramita Sulu, Bukunmi Adediran, Hongmin Tu, Antti M. Salo, Sudarshan Murthy, Johanna Myllyharju, Rik K. Wierenga, M. Kristian Koski   +8 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source