Results 61 to 70 of about 33,521 (167)

Dual Effects of β‐TrCP2 Deletion in Bone Homeostasis: Suppression of Osteoclastogenesis and Enhancement of Osteoblast Activity

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to elucidate the role of beta‐transducin repeat‐containing protein 2 (β‐TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. Methods The role of β‐TrCP2 in bone phenotypes was investigated using systemic β‐TrCP1 knockout (KO) and β‐TrCP2KO mice, along with myeloid‐specific ...
Woo Jung Kim, Sora Han, Hye In Ka, Sun Young Lee, Jiwon Kim, Hyunjeong Joo, Sujung Soh, Gaeun Oh, Kyung Hyun Yoo, Seung Hyun Han, Yeongkag Kwon, Choogon Lee, Kyung‐Hyun Park‐Min, Se Hwan Mun, Young Yang   +14 more
wiley   +1 more source

Computational-Experimental Characterization of Transcranial Magneto-Acoustic Stimulation for Dose-Efficient Neural Activation. [PDF]

Brain Sci
Tan R, Chu F, Wang X, Zhou X, Ma R, Yin T, Fan H, Liu Z.   +7 more
europepmc   +1 more source

Spatial Proteomics Identifies Distinct Synovial Microenvironments in Hip and Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a heterogeneous joint disease, yet mechanistic insights derive predominantly from knee OA and are often extrapolated to other joints. We investigated joint‐associated differences in the spatial molecular organization of hip and knee OA synovium.
Peng Xie, Antonia R. Sun, Zhengtan Zheng, Yunkun Qu, Feng Gao, Christina Theodoropoulos, Nicholas Matigian, Zhiyong Li, Ross Crawford, Indira Prasadam   +9 more
wiley   +1 more source

Integrative bioinformatics analysis identifies gut microbiota-derived metabolite-associated immune candidate targets in high-risk primary biliary cholangitis. [PDF]

PLoS One
Feng J, Liu Z, Sun H.
europepmc   +1 more source

Optimization of acid‐catalyzed transesterification of oil derived from mango processing seed waste: a step towards the circular economy

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Energy is the basis for socio‐economic development. The effects of fossil‐based energy sources underscore the urgent need for renewable and cost‐effective alternatives. Biofuels derived from non‐edible and low‐cost feedstocks are a promising alternative.
Getachew D. Gebre, Shemelis N. Gebremariam, Yadessa G. Keneni, Jorge M. Marchetti   +3 more
wiley   +1 more source

Single-Cell Transcriptomics Reveals the Immune Pathogenesis of Isolated Coronary Arteritis Presenting as Refractory In-Stent Restenosis. [PDF]

JACC Basic Transl Sci
Yu M, Jiang Y, Huang J, Wei ZY, Song ZF, Tan FS, Huang SZ, Yuan JS, Ye SD, Cui JG, Zhao HJ, Gao LJ, You HZ, Zeng Y, Yang WX, Qian HY.   +15 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Physical restraint induces conditioned place aversion and region-specific c-Fos activation in mice. [PDF]

Neurosci Lett
Reinders E, Tondravi M, Lee SR, Beyene E, Nguyen T, LeGates TA.   +5 more
europepmc   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

Designing Threefold π‐Surfaces Through Peripheral Halogenation to Shape Multidirectional Molecular Packing

Chemistry – A European Journal, EarlyView.
The complete series of hexahalogenated triptycene‐tribenzoquinones, comprising newly synthesized fluoro‐, bromo‐, and iodo‐substituted derivatives together with the previously reported chloro analogue, enables systematic comparison of their molecular properties and intermolecular interactions in relation to their crystal packing modes.
Shuta Tsuruga, Kenzo Suzuki, Hiromichi Yokoyama, Yoshiaki Shoji, Takanori Fukushima   +4 more
wiley   +1 more source