Germacrone suppresses renal cancer growth by regulating c-Fos-mediated lipid metabolism. [PDF]
Wang B +9 more
europepmc +1 more source
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
In-Silico discovery of Pediatric Acute-Myeloid-Leukemia (pAML) causing druggable molecular signatures highlighting their pathogenetic processes and therapeutic agents through single-cell RNA-Seq profile analysis. [PDF]
Ahmed MF +10 more
europepmc +1 more source
Review of Catenary Icing on High‐Speed Railways: Characteristics, Impact and Countermeasures
ABSTRACT The pantograph–catenary system (PCS) is the only path for electrified railway trains to acquire energy. Catenary icing during winter is a common natural phenomenon, which usually leads to the deterioration of the current quality and severely affects the operational safety of trains.
Zheng Li +7 more
wiley +1 more source
Involvement of the hypothalamus-raphe magnus-spinal defecation center axis in stress-induced defecation in rats. [PDF]
Yuki N +6 more
europepmc +1 more source
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima +4 more
wiley +1 more source
Regulation of Embryonic Wound Healing by Matrix Metalloproteinases in Xenopus laevis Tailbud Stage. [PDF]
Kraus D +5 more
europepmc +1 more source
We reanalyzed our XFEL data, the results of which showed the insertion of O6 during the S2–S3 transition in water oxidation by photosystem II. These results contradict the interpretation proposed by Wang that there is no insertion of O6 during the S2–S3 transition.Photosystem II (PSII) catalyzes the light‐driven oxidation of water to molecular oxygen ...
Hongjie Li +2 more
wiley +1 more source
Photochemical nanomotors reverse anxiety- and depressive-related behaviors in rodents via spatiotemporal polarity dynamics tuning. [PDF]
Chen B +10 more
europepmc +1 more source
Abstract Foregrounding the role of finance, this article examines the historical production and future trajectory of the urban water crisis in Mombasa. Drawing on archival research and contemporary fieldwork, it traces how principles of full cost recovery—institutionalized during the colonial period and later reworked through postcolonial ...
Joe Williams
wiley +1 more source

