Identification of PECAM1 as a Prognostic Biomarker for Lung Adenocarcinoma. [PDF]
Lin SS+5 more
europepmc +1 more source
ABSTRACT Recently, a distinct subgroup of vascular neoplasms has been identified, characterized by NFATC‐related fusions. Although existing literature is limited, these lesions histologically show a variable appearance with a tendency for local recurrence but not distant spread.
B. Schurink+3 more
wiley +1 more source
Temporal interference stimulation over the motor cortex enhances cortical excitability in rats. [PDF]
Nguyen TXD+6 more
europepmc +1 more source
Circulating Fetuin‐A concentrations in rheumatic diseases: a systematic review and meta‐analysis
In this systematic review with meta‐analysis, we identified 19 eligible studies to determine whether there is any change in Fetuin‐A (FtA) concentrations in patients with rheumatic diseases. We observed a significant decrease in FtA concentrations in RD patients (standardized mean difference, SMD = −.91; 95% CI −1.43 to −.39, p = .001).
Biagio Di Lorenzo+6 more
wiley +1 more source
Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression. [PDF]
Aboharb F+11 more
europepmc +1 more source
Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya+4 more
wiley +1 more source
Can activator protein-1 transcription factors be monitored in the maternal circulation to predict set on labor? [PDF]
Yahyayev T+3 more
europepmc +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva+14 more
wiley +1 more source
Interim analysis of the long-term efficacy and safety of azetukalner in an ongoing open-label extension study following a phase 2b clinical trial (X-TOLE) in adults with focal epilepsy. [PDF]
French JA+10 more
europepmc +1 more source
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon+7 more
wiley +1 more source