Results 111 to 120 of about 32,170 (168)

Gut microbiome and metabolome characteristics of patients with cholesterol gallstones suggest the preventive potential of prebiotics. [PDF]

Imeta
Liu Y, Li H, Sun T, Sun G, Jiang B, Liu M, Wang Q, Li T, Cao J, Zhao L, Xiao F, Zhao F, Cui H.   +12 more
europepmc   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition

Immunology, EarlyView.
Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen, Burcu Al, Thomas Ulas, Nico Reusch, Harsh Bahrar, Siroon Bekkering, Jaydeep Bhat, Dieter Kabelitz, Joachim L. Schultze, Frank L. van de Veerdonk, Jeanine Roeters van Lennep, Niels P. Riksen, Leo A. B. Joosten, Mihai G. Netea, Katarzyna Placek   +14 more
wiley   +1 more source

Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation. [PDF]

Nat Commun
Cadefau-Fabregat M, Martínez-Cebrián G, Lorenzi L, Weiss FD, Frank AK, Castelló-García JM, Julià-Vilella E, Gámez-García A, Yera L, de Castro CPM, Wang YF, Meissner F, Vaquero A, Merkenschlager M, Porse BT, Cuartero S.   +15 more
europepmc   +1 more source

The Caring Life Course Theory: Opening new frontiers in care—A cardiac rehabilitation example

Journal of Advanced Nursing, EarlyView.
Abstract Aim(s) To operationalize the Caring Life Course Theory (CLCT) as a framework for improving cardiac rehabilitation (CR) engagement and informing ways to address disparities in rural, low socio‐economic areas. Methods A secondary analysis of data collected from 15 CR programmes to identify CR patterns through the CLCT lens using a mixed‐methods ...
Maria Alejandra Pinero de Plaza, Claire Hutchinson, Alline Beleigoli, Matthew Tieu, Michael Lawless, Tiffany Conroy, Rebecca Feo, Robyn A. Clark, Hila Dafny, Penelope McMillan, Regina Allande‐Cussó, Alison A. Kitson   +11 more
wiley   +1 more source

Radiomics to predict tumor response to combination chemoradiotherapy in squamous cell carcinoma of the anal canal: a preliminary investigation. [PDF]

Eur Radiol Exp
Vanzulli A, Sciacqua LV, Patti F, Drebot R, Montin E, Lattanzi R, Lozza LAM, Villa S, Scaramuzza D.   +8 more
europepmc   +1 more source

Early‐stage randomised controlled trial of therapist‐supported online cognitive therapy for post‐traumatic stress disorder in young people

Journal of Child Psychology and Psychiatry, EarlyView.
Background Effective face‐to‐face treatments for Post‐Traumatic Stress Disorder (PTSD) are available, but most young people with PTSD do not receive effective treatment. Therapist‐supported online Cognitive Therapy has the potential to improve accessibility of effective treatment.
Patrick Smith, Anke Ehlers, Ewan Carr, David M. Clark, Tim Dalgleish, Gordon Forbes, Kimberley Goldsmith, Helena Griffiths, Monica Gupta, Dorothy King, Sarah Miles, Dominic T. Plant, Anne Smith, Jess Steward, William Yule, Richard Meiser‐Stedman   +15 more
wiley   +1 more source

LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis. [PDF]

PLoS One
Zhu L, Meng Q, Qian W, Shao W, Lu Y, Jin S, Zhang A, Yan SG, Lu J.   +8 more
europepmc   +1 more source

Cumulative life course impairment: Evidence for hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Hidradenitis suppurativa (HS) severely affects quality of life, work, relationships and mental health. The cumulative life course impairment (CLCI) model highlights how HS disrupts key life decisions. While long‐term studies are needed, evidence suggests certain factors may help protect patients from these impairments. Abstract Hidradenitis suppurativa
Maneli Doroudian Tehrani, Ruby S. Gibson, Corey L. Snyder, Martina L. Porter, Alexa B. Kimball   +4 more
wiley   +1 more source

Neonatal administration of <i>Lactiplantibacillus plantarum</i> ATCC 202195 with or without fructooligosaccharide in Bangladesh: a placebo-controlled randomized trial. [PDF]

mSphere
Pell LG, Qamar H, Bassani DG, Heasley C, Funk C, Chen C-Y, Shawon J, O'Callaghan KM, Pullenayegum E, Hamer DH, Haque R, Kabir M, Ahmed T, O'Kelly C, Hossain MI, Khan AZ, Loutet MG, Islam MS, Morris SK, Shah PS, Sherman PM, Sultana S, Mahmud AA, Saha SK, Sarker SA, Roth DE.   +25 more
europepmc   +1 more source

Immune Response of Nile Tilapia (Oreochromis niloticus) Vaccinated With Diatom‐Based Oral Vaccines Against Piscine Francisellosis

Journal of Fish Diseases, EarlyView.
ABSTRACT Piscine francisellosis is a highly infectious and economically significant disease caused by Francisella orientalis in tilapia (Oreochromis spp.). There are currently no approved treatments or commercial vaccines for this disease in cultured fish.
Collin Meyer, Roshan P. Shrestha, Ruth Milston‐Clements, Sarah Gibson, Taylor I. Heckman, Zeinab Yazdi, Esteban Soto   +6 more
wiley   +1 more source