Results 81 to 90 of about 32,411 (169)

CXCL10 Promotes Spinal Macrophage Recruitment via the JAK/STAT3 Pathway to Induce Pain in Experimental Autoimmune Prostatitis

Cell Proliferation, Volume 58, Issue 4, April 2025.
The CXCL10/CXCR3 axis was involved in spinal macrophage infiltration through activating the JAK/STAT3 pathway. The prostate NGF/TrKA axis was involved in the neuroinflammation and pain in chronic prostatitis, and inhibition of NGF could attenuate pain response in chronic prostatitis, which provided novel therapeutic targets for pain treatment in ...
Lei Chen, Ziqi Chen, Jia Chen, Hexi Du, Xianguo Chen, Jing Chen, Hui Wang, Chaozhao Liang   +7 more
wiley   +1 more source

Comparing cross-over stenting and focal ostial stenting for ostial left anterior descending coronary artery lesions: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Khairy AM, Hafez AH, Elshahat A, Emara A, Aboueisha H, Fahmy MI, Abdelaziz A, Yasseen I.   +7 more
europepmc   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

Cell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye, Yanlin Li, Xiaolin Yang, Chenglin Li, Rui Yu, Guangjuan Zheng, Zuqing Su   +6 more
wiley   +1 more source

Upregulated CEMIP promotes intervertebral disc degeneration via AP-1-mediated change in chromatin accessibility. [PDF]

Clin Transl Med
Shu S, Zhang X, Feng Z, Liu Z, Wang K, Li F, Wu Y, Shi B, Qiu Y, Zhu Z, Bao H.   +10 more
europepmc   +1 more source

Intelligent Manufacturing for Osteoarthritis Organoids

Cell Proliferation, EarlyView.
Overall schematic of intelligent manufacturing in osteoarthritis organoids. Broad overview of the article's structure, outlining the progression from fundamental joint anatomy and OA pathogenesis to organoid construction and, ultimately, to intelligent manufacturing and future prospects.
Xukun Lyu, Jian Wang, Jiacan Su
wiley   +1 more source

GluR2 overexpression in ACC glutamatergic neurons alleviates cancer-induced bone pain in rats. [PDF]

Mol Med
Ba F, Wei J, Feng QY, Yu CY, Song MX, Hu S, Xu GY, Zhang HL, Jiang GQ.   +8 more
europepmc   +1 more source

Regulating the Plasticity of Hippocampal Neurons via Electroacupuncture in Depression Model Mice

Cell Proliferation, EarlyView.
This study explores the regulation of the plasticity of hippocampal neurons via electroacupuncture in corticosterone‐induced depression model mice. Electroacupuncture at the Zusanli (ST36) acupoint alleviated depression‐like symptoms and enhanced neuronal plasticity in the hippocampal CA1 region by upregulating BDNF and CaMKIIβ, highlighting its ...
Yiyang Wang, Xinyi Du, Chenxi Duan, Miaomiao Wang, Ying Zhu, Lihua Wang, Jun Hu, Yanhong Sun   +7 more
wiley   +1 more source

Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course. [PDF]

Circ Genom Precis Med
Urbut SM, Cho SMJ, Paruchuri K, Truong B, Haidermota S, Peloso GM, Hornsby WE, Philippakis A, Fahed AC, Natarajan P.   +9 more
europepmc   +1 more source

Circulating Fetuin‐A concentrations in rheumatic diseases: a systematic review and meta‐analysis

European Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
In this systematic review with meta‐analysis, we identified 19 eligible studies to determine whether there is any change in Fetuin‐A (FtA) concentrations in patients with rheumatic diseases. We observed a significant decrease in FtA concentrations in RD patients (standardized mean difference, SMD = −.91; 95% CI −1.43 to −.39, p = .001).
Biagio Di Lorenzo, Stefano Zoroddu, Arduino A. Mangoni, Panagiotis Paliogiannis, Gian Luca Erre, Ciriaco Carru, Angelo Zinellu   +6 more
wiley   +1 more source

c-FOS Confers Stem Cell-like Features to Multiple Myeloma Cells in a Bone Marrow Microenvironment. [PDF]

Cells
Osada N, Kikuchi J, Matsuoka S, Yasui H, Ikeda S, Takahashi N, Furukawa Y, Nakasone H.   +7 more
europepmc   +1 more source