Results 91 to 100 of about 4,222 (191)

Expanding the Phenotype of CYFIP2‐Related Developmental Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pathogenic CYFIP2 variants cause developmental and epileptic encephalopathy (DEE), characterized by early‐onset intractable epilepsy and developmental delay. The disease course has not been delineated. Codon Arg87 is a de novo mutational hotspot associated with a severe DEE phenotype via gain‐of‐function mechanisms. Currently, there
Michaela Squire, Jenna K. Lea, Zheng (Jane) Fan, Senyene E. Hunter   +3 more
wiley   +1 more source

Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region. [PDF]

PLoS One
Kubota A, Kojima K, Koketsu S, Kannon T, Sato T, Hosomichi K, Shinohara Y, Tajima A.   +7 more
europepmc   +1 more source

Board Composition, Sustainability Reporting, and the Moderating Role of a Contextual Issue: Evidence From an Emerging Country

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the impact of board composition (BC) on sustainability reporting (SR) in financial firms listed on the Dhaka Stock Exchange (DSE), with a focus on the moderating role of non‐performing loans (NPLs). Using 421 firm‐year observations from 49 firms (2016–2024) and an ordinary least squares (OLS) regression model, the results ...
Sumon Kumar Das, Prome Akter
wiley   +1 more source

Identification of neural crest and melanoma cancer cell invasion and migration genes using high‐throughput screening and deep attention networks

Developmental Dynamics, EarlyView.
Abstract Background Cell migration and invasion are well‐coordinated in development and disease but remain poorly understood. We previously showed that the neural crest (NC) cell migratory wavefront shares a 45‐gene panel with other cell invasion phenomena.
J. C. Kasemeier‐Kulesa, S. Martina Perez, R. E. Baker, P. M. Kulesa   +3 more
wiley   +1 more source

Rational Design and Operando Characterization of Hierarchical α‐FeOOH‐FeP/Ni3S2 Catalysts for High‐Rate Alkaline Water Electrolysis

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A hierarchical FeOOH–FeP@Ni3S2 electrocatalyst is engineered on 3D Ni foam to enable efficient alkaline oxygen evolution. Operando spectroscopic techniques reveal dynamic surface reconstruction and proton‐coupled electron transfer (PCET) kinetics. The catalyst exhibits low overpotential and industrial‐level current operation, driving high‐performance ...
Maria S. Metaxa, Ioannis Vamvasakis, Gerasimos S. Armatas   +2 more
wiley   +1 more source

Soybean Oil, Linseed Oil, Brazil Nut Oil and Fish Oil Supplementation in European Quails Diet: Lipid and Protein Oxidative Stability of Meat During Storage

European Journal of Lipid Science and Technology, EarlyView.
European quails were fed diets containing soybean oil, linseed oil, Brazil nut oil, fish oil, and their other mixes. After 60 days of frozen storage, quail breast meat from birds receiving Brazil nut oil (alone or combined with soybean oil) exhibited the greatest oxidative stability, maintaining color and reducing lipid and protein oxidation markers ...
Janiele Ferreira da Silva, Cristiani Viegas Brandão Grisi, Cecylyana Leite Cavalcante, Valquíria Cardoso Da Silva Ferreira, Bruno Raniere Lins de Albuquerque Meireles, José Jordão Filho, Leonardo Augusto Fonseca Pascoal   +6 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Efficacy and safety of perampanel as first adjunctive therapy in patients with focal‐onset seizures or generalized tonic‐clonic seizures in four post‐marketing studies across regions

Epilepsia Open, EarlyView.
Abstract Objective Early response to anti‐seizure medication (ASM) is associated with a favorable prognosis in patients with epilepsy. Research is required to confirm existing data on the clinical use of perampanel as first adjunctive therapy in different patient groups and different regions.
Stefano Meletti, Vineet Punia, Amitabh Dash, Anna Lisa Gentile, Ricardo Sáinz‐Fuertes, Samantha Goldman, Tobias Goldmann, Anna Patten, Dinesh Kumar, Leock Y. Ngo, Bernhard J. Steinhoff   +10 more
wiley   +1 more source

Multi‐Scale Evolution Mechanism of Water‐Conducting Fracture Zone in Deep‐Mining Hard Roof

Energy Science &Engineering, EarlyView.
ABSTRACT This study addresses the significant discrepancies in traditional methods for predicting the height of water‐conducting fracture zones in deep‐mining hard roofs, which can lead to catastrophic water inrush events. The 110,504 working face of Banji Coal Mine was chosen as the research site to systematically investigate the development ...
Yingfu Li, Linyang Bai, Hongwei Cai, Di Hu, Fangang Zeng   +4 more
wiley   +1 more source