Results 71 to 80 of about 4,076 (169)

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

Annals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang, Taylor L. Charron, Min Fu, Miranda Dunn, Deborah M. Jones, Praveen Kumar, Satoshi Ishishita, Allan‐Hermann Pool, Ashwinikumar Kulkarni, Genevieve Konopka, Vikram G. Shakkottai   +10 more
wiley   +1 more source

Inside the head of Crotalus durissus LINNAEUS, 1758 (Serpentes, Viperidae, Crotalinae): Macroscopic description of the brain with ontogenetic insights

The Anatomical Record, EarlyView.
Abstract Neuroanatomy studies in vertebrates have garnered significant attention in recent years, particularly driven by advancements in computerized tomography imaging techniques. Nonetheless, these advancements remain largely constrained to specific vertebrate groups, notably mammals, birds, and fish, leaving studies in reptiles at an incipient stage.
Giordanna Issa Lucas, Angele Martins
wiley   +1 more source

Description of the skull, braincase, and dentition of Moschognathus whaitsi (Dinocephalia, Tapinocephalia), and its palaeobiological and behavioral implications

The Anatomical Record, EarlyView.
Abstract A subadult Moschognathus whaitsi from the Eastern Cape Province, South Africa, was scanned using synchrotron radiation X‐ray computed tomography (SRXCT). Its subadult state allowed the cranial bones and teeth to be identified and individually reconstructed in 3D.
Tristen Lafferty, Luke A. Norton, Aliénor Duhamel, Julien Benoit   +3 more
wiley   +1 more source

Multi‐Omics Insights Into the Role of Fructooligosaccharides Supplementation in Alleviating Salpingitis in Laying Hens

Animal Research and One Health, EarlyView.
Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song, Tao Duan, Rong Li, Xiaoqiu Wang, Fengdong Zhang, Jia Feng, Lin Qiao, Junlin Cheng, Lixian Chen, Aike Li, Yuna Min, Weiwei Wang   +11 more
wiley   +1 more source

JWST Imaging of the Closest Globular Clusters—VI. The Lowest‐Mass Objects in M 4 and the Galactic Bulge

Astronomische Nachrichten, EarlyView.
ABSTRACT We present James Webb Space Telescope observations of M 4—the closest globular cluster—that probe the lower Main Sequence down to the hydrogen‐burning limit. The unveiled stellar sequence reaches much fainter luminosities than previously possible, revealing a few extremely red objects that are consistent with brown dwarfs as cool as Teff∼1000K$
L. R. Bedin, R. Gerasimov, A. Calamida, M. Libralato, M. Scalco, D. Nardiello, M. Griggio, D. Apai, J. Anderson, A. Bellini, A. Burgasser   +10 more
wiley   +1 more source

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

Autism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin, Samantha M. Matta, Julia E. Dallman, Suzanne Hosie, Manon Moreau, Ashley E. Franks, Thomas Bourgeron, Elisa L. Hill‐Yardin   +7 more
wiley   +1 more source

The Effect of Self‐Concept Components on Sustainable Food Choice

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite the growing global adoption of sustainable food consumption, the role of self‐concept (including self‐esteem, self‐image, and ideal self) and mindset (beliefs about personal growth and adaptability) in shaping these choices remains underexplored.
Hassan Rahnama Haratbar, Peter T. L. Popkowski Leszczyc, Claudia Gonzalez‐Arcos   +2 more
wiley   +1 more source

A noncanonical parasubthalamic nucleus-to-extended amygdala circuit converts chronic social stress into anxiety. [PDF]

J Clin Invest
Liu N, Wang J, Wang H, Gao B, Lin Z, Xu TL, Duan S, Xu H.   +7 more
europepmc   +1 more source

Shades of Green Labeling: A Bibliometric Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT Sustainability labels are a signal of firms' commitment to environmental, social, and governance (ESG) related goals and can be driven by firms' ESG strategy. There is a multitude of labeling schemes leading to calls for either a simplified, overarching sustainability label or greater harmonization across the existing labels.
Roopali Bhatnagar, Malgorzata Krzywonos, Agnieszka Piekara, Efthymios Altsitsiadis   +3 more
wiley   +1 more source

Dopamine D2 receptor modulating mPFC-BLA circuit contributes to chronic sleep deprivation-induced memory impairment in mice. [PDF]

Theranostics
Yang J, Sun J, Liu Z, Tang X, Hu Y, Shen W, Xie Y, Jin Y, Li H, Li X, Jiang Y, Chan MTV, Wu WKK, Liu Z, Liu X, Hu Y, Zhu J, Ma D.   +17 more
europepmc   +1 more source