Results 171 to 180 of about 517 (218)
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Bromocriptine and the expression of c-myc and c-fos in human prolactinomas
Neurological Research, 2001Prolactinomas are one of the most frequent tumors of the human anterior pituitary. Dopamine agonists are the choice in the medical treatment of this disease. Bromocriptine (BC) is a well known anti-neoplasic agent in human PRL secreting adenomas although its effect on PRL cells is far from clear.
J A, Burdman +3 more
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Transcriptional activation of cellular oncogenes fos, jun, and myc by human cytomegalovirus
Journal of Virology, 1991The mechanisms responsible for the human cytomegalovirus (HCMV)-induced increase in cellular oncogene RNAs for c-jun, c-fos, and c-myc in human embryo lung cells (I. Boldogh, S. AbuBakar, and T. Albrecht, Science 247:561-564, 1990) were investigated.
I, Boldogh +3 more
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A STUDY ON THE ONCOGENES GLI, FOS, JUN AND MET IN HUMAN UTERINE LEIOMYOMAS
International Journal of Oncology, 1994122 human uterine leiomyomas, representing the main chromosomal aberrations seen in these tumours, were analyzed by Southern blotting. Probes for the four oncogenes, gli, fos, jun, and met, all localized in or close to the chromosomal breakpoints in leiomyomas, were used.
G, Havel +4 more
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Progestin modulation of c-fos and prolactin gene expression in the human endometrium
Fertility and Sterility, 1999To evaluate the influence of the menstrual cycle and the effects of medroxyprogesterone acetate (MPA) on the expression of the protooncogene c-fos and of prolactin (PRL) in the human endometrium in vivo.Double-blind, placebo-controlled trial.Healthy volunteers in an academic research environment.Regularly cycling women who were not taking hormonal ...
F M, Reis +3 more
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Overexpression ofc-Ki-ras andc-fos in human pancreatic carcinomas
International journal of pancreatology, 1992The mRNA expression of protooncogenes c-Ki-ras, c-myc, and c-fos was studied in five pancreatic carcinomas and five normal pancreatic tissues using RNase protection assay and Northern blot analysis. The expression of those protooncogenes was detected in total mRNA from all specimens. However, the amounts in carcinomas and in normal tissues differed.
K, Wakita +4 more
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The gene structure of the Drosophila melanogaster homolog of the human proto-oncogene fos
Gene, 2001The Drosophila melanogaster homolog of the human proto-oncogene fos is Dfos. It is the only fos homolog in the Drosophila genome. Fos functions as a subunit of the heterodimeric transcription factor AP-1. There are two models of the Dfos gene. The first comes from a cDNA sequence of Dfos (Perkins et al., Genes Dev. 4 (1990) 822). The second is from the
E, Rousseau, E S, Goldstein
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c-Fos protooncogene expression in human normal peripheral blood leukocytes
Cytotechnology, 1987The aim of this study was to investigate the expression of c-fos protooncogene in normal human peripheral blood leukocytes by Northern blot analysis. Unlike lymphoid cells, monocytes express appreciable levels of c-fos transcripts. Unexpectedly, unlike HL-60 (promyelocytic)-derived granulocytes, freshly isolated polymorphonuclear cells (PMN) showed c ...
F, Colotta +3 more
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Overexpression of c-fos increases recombination frequency in human osteosarcoma cells
Carcinogenesis, 1993We have shown previously that overexpression of c-Ha-ras, v-mos or c-fos increases the spontaneous level of chromosomal aberrations and gene mutations in NIH 3T3 cells, and that reduction of the Fos protein level inhibits aberration induction by c-Ha-ras and v-mos and also by irradiation with ultraviolet light (van den Berg et al., Mol. Carcinogenesis,
den Berg, S. van +3 more
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Negative regulation of human c-fos expression by thes retinoblastoma gene product
Nature, 1990Inactivation of the retinoblastoma susceptibility gene (RB-1) has been associated with the aetiology of many types of human cancers, leading to the classification of RB-1 as an anti-oncogene or tumour suppressor gene. Given that the protein product of RB-1 (Rb) has a nuclear localization and DNA-binding activity in vitro, it is possible that Rb ...
P D, Robbins +2 more
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c-jun and c-fos are expressed by human megakaryocytes.
Experimental hematology, 1992Expression of the main nuclear protooncogenes during terminal megakaryocyte (MK) differentiation is poorly understood. Because previous results have suggested that c-fos and c-jun protooncogenes are expressed in human leukemic cell lines induced to undergo megakaryocytic differentiation, we have analyzed the expression of these two protooncogenes in ...
M A, Mouthon +4 more
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