Results 1 to 10 of about 78,532 (208)

Targeting the senescence-related genes MAPK12 and FOS to alleviate osteoarthritis

Journal of Orthopaedic Translation
Background: The mechanism by which chondrocyte senescence aggravate OA progression has not yet been well elucidated. The aim of this study was to investigate the chondrocyte senescence related gene biosignatures in OA, and to analyze on the underlying ...
Nana Geng, Menglin Xian, Lin Deng, Biao Kuang, Yiming Pan, Kaiwen Liu, Yuanlan Ye, Mengtian Fan, Zhixun Bai, Fengjin Guo   +9 more
doaj   +4 more sources

FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes

Cells, 2021
The transcription factor SOX2 is important for brain development and for neural stem cells (NSC) maintenance. Sox2-deleted (Sox2-del) NSC from neonatal mouse brain are lost after few passages in culture.
Miriam Pagin, Mattias Pernebrink, Mattia Pitasi, Federica Malighetti, Chew-Yee Ngan, Sergio Ottolenghi, Giulio Pavesi, Claudio Cantù, Silvia K. Nicolis   +8 more
doaj   +3 more sources

Fos Facilitates Gallid Alpha-Herpesvirus 1 Infection by Transcriptional Control of Host Metabolic Genes and Viral Immediate Early Gene

Viruses, 2021
Gallid alpha-herpesvirus 1, also known as avian infectious laryngotracheitis virus (ILTV), continues to cause huge economic losses to the poultry industry worldwide.
Zhitao Wang, Yangyang Qiao, Zhijie Chen, Yumeng Liang, Lu Cui, Yanhui Zhang, Xuefeng Li, Li Xu, Ping Wei, Shengwang Liu, Hai Li   +10 more
doaj   +2 more sources

A transcriptome map of cellular transformation by the fos oncogene

Molecular Cancer, 2005
Background The c-fos gene was originally identified as the cellular homolog of the oncogene v-fos carried by the Finkel-Biskis-Jenkins and Finkel-Biskis-Reilly murine osteogenic sarcoma retroviruses.
Ruan Hong, Fenster Steven D, Ordway Jared M, Curran Thomas   +3 more
doaj   +2 more sources

Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

BMC Genomics, 2008
Background Dietary non-digestible carbohydrates stimulate the gut microflora and are therefore presumed to improve host resistance to intestinal infections.
Kramer Evelien, Keijer Jaap, Rodenburg Wendy, Vink Carolien, van der Meer Roelof, Bovee-Oudenhoven Ingeborg MJ   +5 more
doaj   +2 more sources

Current Opinion on the Use of c-Fos in Neuroscience

NeuroSci, 2022
For years, the biochemical processes that are triggered by harmful and non-harmful stimuli at the central nervous system level have been extensively studied by the scientific community through numerous techniques and animal models.
Sandra Yasbeth Lara Aparicio, Ángel de Jesús Laureani Fierro, Gonzalo Emiliano Aranda Abreu, Rebeca Toledo Cárdenas, Luis Isauro García Hernández, Genaro Alfonso Coria Ávila, Fausto Rojas Durán, María Elena Hernández Aguilar, Jorge Manzo Denes, Lizbeth Donají Chi-Castañeda, César Antonio Pérez Estudillo   +10 more
doaj   +2 more sources

Abnormal c-Fos expression in TetTag mice containing fos-EGFP [PDF]

Frontiers in Behavioral Neuroscience
Molecular and genetic techniques now allow selective tagging and manipulation of the population of neurons, often referred to as “engram cells,” that were active during a specific experience.
Jacob H. Wilmot, Jacob H. Wilmot, Tracy L. Warren, Tracy L. Warren, Tracy L. Warren, Cassiano R. A. F. Diniz, Deger Carda, Deger Carda, Marrisa M. Lafreniere, Alex S. Nord, Alex S. Nord, Alex S. Nord, Brian J. Wiltgen, Brian J. Wiltgen   +13 more
doaj   +4 more sources

Identification of signature genes for renal ischemia‒reperfusion injury based on machine learning and WGCNA

Heliyon, 2023
Background: As an inevitable event after kidney transplantation, ischemia‒reperfusion injury (IRI) can lead to a decrease in kidney transplant success. The search for signature genes of renal ischemia‒reperfusion injury (RIRI) is helpful in improving the
Zechao Lu, Senkai Xu, Haiqin Liao, Yixin Zhang, Zeguang Lu, Zhibiao Li, Yushu Chen, Feng Guo, Fucai Tang, Zhaohui He   +9 more
doaj   +1 more source

Expression of CCL2, FOS, and JUN May Help to Distinguish Patients With IgA Nephropathy From Healthy Controls

Frontiers in Physiology, 2022
BackgroundIgA nephropathy (IgAN), the most common type of glomerulonephritis worldwide, can only be diagnosed mainly by renal biopsy owing to lack of effective biomarkers.
Xue Zhou, Xue Zhou, Xue Zhou, Ning Wang, Yuefeng Zhang, Pei Yu, Pei Yu   +6 more
doaj   +1 more source

Fosfomycin resistance mechanisms in Enterobacterales: an increasing threat

Frontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is well-known to be a global health and development threat. Due to the decrease of effective antimicrobials, re-evaluation in clinical practice of old antibiotics, as fosfomycin (FOS), have been necessary.
Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Jaroslav Hrabak, Jaroslav Hrabak, Ibrahim Bitar, Ibrahim Bitar   +6 more
doaj   +1 more source