Results 21 to 30 of about 78,532 (208)

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Peripheral Mononuclear Cells in Patients With Ankylosing Spondylitis

Frontiers in Immunology, 2021
ObjectiveGenetic studies on ankylosing spondylitis (AS) have identified more than 100 pathogenic genes. Building a bridge between these genes and biologically targeted therapies is the current research hotspot.MethodsWe integrated single-cell assaying ...
Huixuan Xu, Haiyan Yu, Lixiong Liu, Hongwei Wu, Cantong Zhang, Wanxia Cai, Xiaoping Hong, Dongzhou Liu, Donge Tang, Yong Dai, Yong Dai   +10 more
doaj   +1 more source

Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21^WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]

, 2008
To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Chan, W-C., Wu, H., Weng-Chyn Chan, Alexander, C.L., Yao, D., Claire L. Alexander, Jean A. Quinn, Hong Wu, David A. Greenhalgh, Greenhalgh, D.A., Quinn, J., Denggao Yao   +11 more
core   +1 more source

Central and Peripheral Changes in FOS Expression in Schizophrenia Based on Genome-Wide Gene Expression

Frontiers in Genetics, 2019
Schizophrenia is a chronic, debilitating neuropsychiatric disorder. Multiple transcriptomic gene expression profiling analysis has been used to identify schizophrenia-associated genes, unravel disease-associated biomarkers, and predict clinical outcomes.
Jing Huang, Jing Huang, Fangkun Liu, Bolun Wang, Hui Tang, Hui Tang, Ziwei Teng, Ziwei Teng, Lehua Li, Lehua Li, Yan Qiu, Yan Qiu, Haishan Wu, Haishan Wu, Jindong Chen, Jindong Chen   +15 more
doaj   +1 more source

Carcase traits, meat quality, and lipogenic gene expression in muscle of lambs fed wheat bran feruloyl oligosaccharides

Italian Journal of Animal Science, 2023
This study investigated the effects of dietary feruloyl oligosaccharides derived from fermented wheat bran (FOs-FWB) supplementation on carcase traits, meat quality, muscle fatty acid composition, and the expression of lipogenic genes in lambs.
Yuchao Hu, Ziqi Meng, Wenwen Wang, Xiran Hao, Yuan Wang, Jingwei Qi   +5 more
doaj   +1 more source

The function of heterodimeric AP-1 comprised of c-Jun and c-Fos in activin mediated Spemann organizer gene expression.

PLoS ONE, 2011
BackgroundActivator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific role of AP-1 in activin signaling has not been elucidated during vertebrate development.Methodology/principal findingsWe provide ...
Sung-Young Lee, Jaeho Yoon, Hyun-Shik Lee, Yoo-Seok Hwang, Sang-Wook Cha, Chul-Ho Jeong, Jong-Il Kim, Jae-Bong Park, Jae-Yong Lee, SungChan Kim, Mae Ja Park, Zigang Dong, Jaebong Kim   +12 more
doaj   +1 more source

Incorporation of Fructooligosaccharides in Diets Influence Growth Performance, Digestive Enzyme Activity, and Expression of Intestinal Barrier Function Genes in Tropical Gar (Atractosteus tropicus) Larvae

Fishes, 2022
This study was conducted to investigate the effects of dietary fructooligosaccharides (FOS) on the growth, survival rate, digestive enzyms activity, and the expression of intestinal barrier function genes in tropical gar (Atractosteus tropicus) larvae. A
Graciela M. Pérez-Jiménez, Emyr Saul Peña-Marín, Claudia I. Maytorena-Verdugo, Cesar Antonio Sepúlveda-Quiroz, Luis Daniel Jiménez-Martínez, Susana De la Rosa-García, Gloria Gertrudys Asencio-Alcudia, Rafael Martínez, Dariel Tovar-Ramírez, Mario A. Galaviz, Talhia Martínez-Burguete, Carlos A. Alvarez-González, Carina Shianya Alvarez-Villagomez   +12 more
doaj   +1 more source

Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes

Cell Reports, 2019
Summary: Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes.
Liang-Fu Chen, Yen Ting Lin, David A. Gallegos, Mariah F. Hazlett, Mariana Gómez-Schiavon, Marty G. Yang, Breanna Kalmeta, Allen S. Zhou, Liad Holtzman, Charles A. Gersbach, Jörg Grandl, Nicolas E. Buchler, Anne E. West   +12 more
doaj   +1 more source

An autophagy-related diagnostic biomarker for uterine fibroids: FOS

Frontiers in Medicine, 2023
Uterine fibroids (UFs) are the most common benign gynecologic tumors in reproductive-aged women. The typical diagnostic strategies of UFs are transvaginal ultrasonography and pathological feature, while molecular biomarkers are considered conventional ...
Lei Cai, Jie Li, Rui Long, Zhiqi Liao, Juejun Gong, Bowen Zheng, Hanwang Zhang   +6 more
doaj   +1 more source

The local transcriptional regulators SacR1 and SacR2 act as repressors of fructooligosaccharides metabolism in Lactobacillus plantarum

Microbial Cell Factories, 2020
Background In Lactobacillus plantarum, fructooligosaccharides (FOS) metabolism is controlled by both global and local regulatory mechanisms. Although catabolite control protein A has been identified as a global regulator of FOS metabolism, the functions ...
Chen Chen, Linlin Wang, Haiyan Yu, Huaixiang Tian   +3 more
doaj   +1 more source

Transcriptional activation encoded by the v-fos gene. [PDF]

Proceedings of the National Academy of Sciences, 1986
We present evidence that the fos oncogene encodes a transcriptional trans-activation function. trans-activation was assayed by cotransfection into NIH 3T3 mouse fibroblasts of v-fos DNA containing plasmids together with a plasmid containing a test promoter.
C, Setoyama, R, Frunzio, G, Liau, M, Mudryj, B, de Crombrugghe   +4 more
openaire   +2 more sources