Results 41 to 50 of about 140,486 (305)

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats [PDF]

, 2017
Indexación: Web of Science; Scopus.Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons.
Aguayo, F.I., Aliaga, E., Fiedler, J.L., García-Pérez, A., García-Rojo, G., Muñoz, M., Olave, F.A., Pacheco, A., Parra, C.S., Parra-Fiedler, N.A., Rojas, P.S., Tejos-Bravo, M.   +11 more
core   +2 more sources

Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction

Frontiers in Cardiovascular Medicine
BackgroundThe mortality of patients with acute myocardial infarction (MI) raised rapidly in last decade and obesity are becoming the major cause to CAD progression, thus inducing heart failure preserved ejection fraction (HFpEF).
Ruiying Zhang, Ruiying Zhang, Ruiying Zhang, Man Wang, Man Wang, Man Wang, Yuheng Lang, Yuheng Lang, Jiaqi Zhang, Jiaqi Zhang, Jiaqi Zhang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Han Zheng, Han Zheng, Han Zheng, Yue Zheng, Yue Zheng, Yue Zheng, Yue Zheng, Bingyang Zhou, Bingyang Zhou, Bingyang Zhou   +23 more
doaj   +1 more source

Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension

Frontiers in Physiology, 2021
Objective: Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by thrombofibrotic obstruction of the proximal pulmonary arteries, which result in vascular remodeling of the distal pulmonary artery.
Feng Wang, Feng Wang, Congrui Sun, Xiaoshuo Lv, Xiaoshuo Lv, Mingsheng Sun, Chaozeng Si, Yanan Zhen, Jing Guo, Weiliang Sun, Zhidong Ye, Jianyan Wen, Jianyan Wen, Peng Liu, Peng Liu   +14 more
doaj   +1 more source

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer, Crabbé, Aurélie, LeBlanc, Carly, Mehta, Satish K, Nickerson, Cheryl A, Ott, C Mark, Pierson, Duane L, Stafford, Phillip   +7 more
core   +2 more sources

Screening and Identification of Hub Genes in the Development of Early Diabetic Kidney Disease Based on Weighted Gene Co-Expression Network Analysis

Frontiers in Endocrinology, 2022
ObjectiveThe study aimed to screen key genes in early diabetic kidney disease (DKD) and predict their biological functions and signaling pathways using bioinformatics analysis of gene chips interrelated to early DKD in the Gene Expression Omnibus ...
Ran Wei, Jingtao Qiao, Di Cui, Qi Pan, Lixin Guo   +4 more
doaj   +1 more source

The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]

, 1992
An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas, Johnson, Judith P., Person, Susanne, Ulbrecht, Matthias, Weiss, Elisabeth H.   +4 more
core   +1 more source

Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]

, 2009
Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bamshad, Barrett, Barrett, Brown, C. K. Song, D. Spanswick, D. Wilson, Doi, Enriori, Franklin, Franklin, Garcia, Gottsch, Inagaki, J. G. Mercer, Jamali, Jamali, Leurs, Liu, M. van den Top, Malmlöf, Morgan, Morgan, Morton, Nakamura, Nilaweera, Ookuma, P. Barrett, P. J. Morgan, Panula, Pillot, Prendergast, Revel, Ross, Sakata, Sallmen, Sallmen, Schneider, Song, Spanswick, Spanswick, T. J. Bartness, Top, Tups, Viguié, Yoshimoto, Yoshimura   +46 more
core   +1 more source

Gastrin induces c-fosgene transcription via multiple signaling pathways [PDF]

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1998
We previously observed that the trophic actions of gastrin (G17) on the AR42J rat acinar cell line are mediated by mitogen-activated protein kinase (MAPK)-induced c- fos gene transcription via protein kinase C (PKC)-dependent and -independent pathways.
V M, Stepan, M, Tatewaki, M, Matsushima, C J, Dickinson, J, del Valle, A, Todisco   +5 more
openaire   +2 more sources

Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]

, 1997
Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M., Horowitz, Dr. J.M., Kristal, Dr. M.B., Torres, Dr. G.   +3 more
core  

Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]

, 2006
The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie, Boudou, Alain, Bourdineaud, Jean-Paul, Cuenot, Y., Gauthier, Laury, Gonzalez, Patrice, Mouchet, Florence   +6 more
core   +3 more sources