Results 231 to 240 of about 433,281 (311)

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization. [PDF]

J Biol Chem
Htet M, Estay-Olmos C, Hu L, Wu Y, Powers BE, Campbell CD, Rameshwar A, Ahmed MR, Hohman TJ, Wang Y, Schneider JA, Bennett DA, Menon V, De Jager PL, Kaas GA, Colbran RJ, Greer CB.   +16 more
europepmc   +1 more source

Continuous Subcutaneous Versus Intestinal Levodopa Infusion for Parkinson's Disease: A Real‐World, Monocentric, Observational Study and Critical Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Subcutaneous foslevodopa‐foscarbidopa (SCFF) is a novel, non‐surgical dopaminergic infusion therapy for better controlling motor fluctuations in advanced Parkinson's disease (PD). However, there are scarce real‐world data on efficacy, adverse events and comparisons with other infusion strategies. Objectives Here, we aimed to provide
Johannes Hartig, Lennert Sitzmann, Doreen Hartenstein, Marion Labisch, Chi Wang Ip, Jens Volkmann, Christine Daniels   +6 more
wiley   +1 more source

Oxytocin ameliorates early life stress-induced anxiety-like behavior by normalizing corticotropin-releasing hormone neuron activity in the PVN. [PDF]

iScience
Li C, Xu Y, Lin B, Huang X, Huang Z, Zheng F, Zhu L, Zhu Y, Yang C.   +8 more
europepmc   +1 more source

Professionalization as a Factor of Heterogeneity in Family and Nonfamily Firms: Effects on Performance

Managerial and Decision Economics, EarlyView.
ABSTRACT This study examines the relationship between firm ownership and organizational performance with a focus on heterogeneity in the professionalization of management. Using a comprehensive panel dataset of Spanish manufacturing firms, the study identifies significant ownership‐ and management model‐related differences in productive efficiency. The
Javier Ortiz, Ana F. Gargallo‐Castel
wiley   +1 more source

Different early-life adversity paradigms have disparate effects on maternal care, neuronal activation, and social behavior in developing mice. [PDF]

Neurobiol Stress
Bapat VA, Waters RC, Gordon JK, Gould E.
europepmc   +1 more source

Indirect Striatal Projection Neurons Drive a D2 Receptor‐Dependent Pathway to Dyskinesia and Dystonia

Movement Disorders, EarlyView.
D2 receptor ablation in indirect‐pathway striatal neurons reduces or abolishes dyskinetic and dystonic behaviors induced by L‐DOPA or D2 receptor agonists, respectively. Contralateral turning is reduced, while forward locomotion is increased. These effects are associated with modulation of neuronal activity in dorsal striatum and external globus ...
Laura Andreoli, Teodor Nyman, Elena Espa, Johan Jakobsson, Osama F. Elabi, Maria Angela Cenci   +5 more
wiley   +1 more source

SLC46A1 deficiency-mediated folate restriction suppresses colorectal cancer progression through epigenetic-transcriptional reprogramming. [PDF]

Cell Death Dis
Zhou Y, Liu Y, Liu Y, Che C, Zhao Y, Yu J, Li X, Li A, Chen S, Wang H, Zhou M, Liu D, He W, Wang Z, Han H, Wang X, Lu Y, Wu K, Zhao X.   +18 more
europepmc   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

A stress-activated neuronal ensemble in the supramammillary nucleus produces anxiety-like behavior in male mice. [PDF]

Elife
Zhang J, Yu K, Zhang J, Chang Y, Sun X, Qian Z, Sun Z, Qiao Y, Liu Z, Ren W, Han J.   +10 more
europepmc   +1 more source