Results 281 to 290 of about 499,874 (389)

Fos Expression in Orexin Neurons Varies with Behavioral State

open access: yesJournal of Neuroscience, 2001
I. Estabrooke   +7 more
semanticscholar   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Sequential ultrasound‐driven dynamic control of macrophage polarization combined with hydrogel for mechano‐chemical synergistic tissue repair

open access: yesInterdisciplinary Medicine, EarlyView.
This study presents an innovative therapeutic strategy that integrates sequential ultrasound therapy with an injectable oxidized dextran‐metformin (ODE‐Met) hydrogel to dynamically regulate macrophage polarization and promote angiogenesis for inflamed tissue repair.
Fulong Man   +12 more
wiley   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

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