Results 81 to 90 of about 499,874 (389)

A Brief Introduction to the Transduction of Neural Activity into Fos Signal

Development & Reproduction, 2015
The immediate early gene c-fos has long been known as a molecular marker of neural activity. The neuron’s activity is transformed into intracellular calcium influx through NMDA receptors and L-type voltage sensitive calcium channels.
L. Chung
semanticscholar   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Thick shells and medially wedged posts increase foot orthoses medial longitudinal arch stiffness: an experimental study

Journal of Foot and Ankle Research, 2023
Background Foot orthoses (FOs) are commonly prescribed devices to attenuate biomechanical deficits and improve physical function in patients with musculoskeletal disorders.
Ana Sofia Tavera Pelaez, Nader Farahpour, Ian B. Griffiths, Gabriel Moisan   +3 more
doaj   +1 more source

Incubation of Methamphetamine Craving Is Associated with Selective Increases in Expression of Bdnf and Trkb, Glutamate Receptors, and Epigenetic Enzymes in Cue-Activated Fos-Expressing Dorsal Striatal Neurons

Journal of Neuroscience, 2015
Cue-induced methamphetamine seeking progressively increases after withdrawal (incubation of methamphetamine craving), but the underlying mechanisms are largely unknown.
Xuan Li, F. J. Rubio, Tamara Zeric, J. Bossert, Sarita Kambhampati, H. Cates, P. Kennedy, Qing‐Rong Liu, R. Cimbro, B. Hope, E. Nestler, Y. Shaham   +11 more
semanticscholar   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Ibsen: un escritor burgués en el mundo ácrata

Telondefondo : Revista de Teoría y Crítica Teatral, 2007
Luego de referirse a algunos de los principios fundamentales del pensamiento anarquista, el autor analiza las características que dicho movimiento adquirió en la Argentina de principios de siglo.
Carlos Fos
doaj   +1 more source

Study on Fructooligosaccharide (Fos) Production By Enzyme Pectinex Ultra Sp-l Immobilzed On Alginate [PDF]

, 2017
Fructooligosaccharide (FOS) is a new alternative sweetener with its characteristics such as low energy and safety for people with diabetes.
Nguyen, B. T. (Binh)
core   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

La historia de un monólogo ácrata: "Luchadores" de Isidro Vega y los periplos de una obra de concientización

Telondefondo : Revista de Teoría y Crítica Teatral, 2011
A partir de entrevistas personales realizadas a Isidro Vega y de la recuperación de su monólogo inédito Luchadores, el autor analiza el pensamiento ácrata en Argentina, en el que el teatro adquiere un lugar relevante de propaganda y concientización.
Carlos Fos
doaj   +1 more source

Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons. [PDF]

, 2016
Topoisomerase 1 (TOP1) poisons like camptothecin (CPT) are currently used in cancer chemotherapy but these compounds can have damaging, off-target effects on neurons leading to cognitive, sensory and motor deficits.
Butchbach, Matthew E.R., Gentillon, Cinsley, Harris, Ashlee W., Holbrook, Jennifer, Lumpkin, Casey J., McCahan, Suzanne M., Rossi, Sharyn L., Wang, Wenlan   +7 more
core   +2 more sources