Results 91 to 100 of about 29,630 (214)

The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells [PDF]

open access: yes, 2019
Efflux pumps represent an important and large group of transporter proteins found in all organisms. The importance of efflux pumps resides in their ability to extrude a wide range of antibiotics, resulting in the emergence of multidrug resistance in many
Barras, Frederic   +7 more
core   +3 more sources

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 427-436, June 2026.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron   +6 more
wiley   +1 more source

Efficacy of high doses of intravenous fosfomycin for treatment of urinary tract infection caused by KPC carbapenemase-producing Klebsiella pneumoniae: An observational study

open access: yesJournal of Global Antimicrobial Resistance
: Objective: To evaluate the efficacy of high-dose intravenous fosfomycin for the treatment of urinary tract infections (UTI) caused by KPC carbapenemase-producing Klebsiella pneumoniae (KPC-Kp).
Jorge Rodríguez-Gómez   +14 more
doaj   +1 more source

Exploring dangerous connections between Klebsiella pneumoniae biofilms and healthcare-associated infections [PDF]

open access: yes, 2014
Healthcare-associated infections (HAI) are a huge public health concern,particularly when the etiological agents are multidrug resistant. The ability of bacteria to develop biofilm is a helpful skill, both to persist within hospital units and to ...
Bandeira, Maria   +3 more
core   +2 more sources

Host Factor Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio cholerae

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Antimicrobial stressors, that is, bile or mitomycin C, induce enlarged, nucleic acid‐rich bacterial extracellular vesicles in Vibrio cholerae that facilitate horizontal gene transfer in vitro and during intestinal colonisation. The findings provide a detailed comparison of control versus stress‐induced vesicles, identify bile as a host factor shaping ...
Dominik Fleischhacker   +6 more
wiley   +1 more source

Prevalence and Relatedness of Salmonella in the Environments of Livestock Markets Handling Surplus Dairy Calves

open access: yesZoonoses and Public Health, Volume 73, Issue 3, Page 169-180, May 2026.
ABSTRACT Introduction Livestock markets are critical hubs within animal trade networks that influence pathogen dissemination at the regional and national scale. Indeed, a 2016 Salmonella serovar Heidelberg outbreak, initially linked to surplus dairy calves at livestock markets, sickened 63 people across 17 states.
Samantha R. Locke   +6 more
wiley   +1 more source

The Role of Bacillithiol in Gram-Positive Firmicutes [PDF]

open access: yes, 2018
Significance: Since the discovery and structural characterization of bacillithiol (BSH), the biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent detoxification enzymes (FosB, Bst, GlxA/B) have been explored in Bacillus and ...
Antelmann, Haike   +3 more
core   +1 more source

One Health Genomic Analysis of Methicillin‐Resistant Staphylococcus spp. From Humans, Cats, and Dogs in a Veterinary Hospital in Central Chile

open access: yesZoonoses and Public Health, Volume 73, Issue 3, Page 205-217, May 2026.
ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido   +7 more
wiley   +1 more source

Characterization of fosS, a novel fosfomycin-modifying enzyme gene identified in Staphylococcus haemolyticus

open access: yesOne Health Advances
The efficacy of fosfomycin is increasingly challenged by emerging resistance mechanisms, primarily involving fosfomycin-modifying enzymes and target (MurA) alterations. This study aimed to elucidate the novel mechanism underlying fosfomycin resistance in
Honghao Huang   +10 more
doaj   +1 more source

Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2016
Fosfomycin is a new agent to Canada approved for the treatment of acute uncomplicated cystitis (AUC) in adult women infected with susceptible isolates of E. coli and Enterococcus faecalis.
George G. Zhanel   +2 more
doaj   +1 more source

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