Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study
Background For treatment of ventriculitis, vancomycin and meropenem are frequently used as empiric treatment but cerebrospinal fluid (CSF) penetration is highly variable and may result in subtherapeutic concentrations.
Christina König +6 more
doaj +1 more source
The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic/pharmacodynamic model [PDF]
There has been a resurgence of interest in aerosolization of antibiotics for treatment of patients with severe pneumonia caused by multidrug-resistant pathogens.
Alan Forrest +64 more
core +1 more source
Local application of gentamicin for wound closure after full‐support microaxial flow pump therapy. ABSTRACT Background Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential ...
Gaik Nersesian +11 more
wiley +1 more source
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi +8 more
wiley +1 more source
Background and Objectives: To assess the effects of fosfomycin compared with other antibiotics as a prophylaxis for urinary tract infections (UTIs) in men undergoing transrectal prostate biopsies. Materials and Methods: We searched multiple databases and
Hui Mo Gu +10 more
doaj +1 more source
Tissue Disposition and Withdrawal Time of Fosfomycin in Swines after Oral and Intramuscular Administration [PDF]
A HPLC-MS/MS method, which was suitable to be used in withdrawal time studies, was validated for the determination of fosfomycin in swine muscle, liver, kidney and skin-fat. Therefore, the withdrawal time of fosfomycin in swines, considering a MRL of 0.5
Pérez, Denisa Soledad +2 more
core +2 more sources
Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui +2 more
wiley +1 more source
Antimicrobial Resistance: We Must Pursue a Collaborative, Global Approach and Use a "One Health" Approach. [PDF]
Treating infection is a key part of the work of most clinicians [...]
Lipman, J, Lonsdale, DO
core +1 more source
Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon +3 more
wiley +1 more source
Complete Genome and Plasmid Sequences of Staphylococcus aureus EDCC 5055 (DSM 28763), Used To Study Implant-Associated Infections [PDF]
Staphylococcus aureus EDCC 5055 (DSM 28763) is a human clinical wound isolate intensively used to study implant-associated infections in rabbit and rat infection models.
Alt, Volker +6 more
core +1 more source

