Results 51 to 60 of about 17,034 (166)

Mutations of the Transporter Proteins GlpT and UhpT Confer Fosfomycin Resistance in Staphylococcus aureus

Frontiers in Microbiology, 2017
With the increasing spread of methicillin-resistant Staphylococcus aureus worldwide, fosfomycin has begun to be used more often, either alone or in combination with other antibiotics, for treating methicillin-resistant S.
Su Xu, Su Xu, Zhuyingjie Fu, Zhuyingjie Fu, Ying Zhou, Ying Zhou, Yang Liu, Yang Liu, Xiaogang Xu, Xiaogang Xu, Minggui Wang, Minggui Wang   +11 more
doaj   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

Australian Endodontic Journal, Volume 52, Issue 2, Page 585-605, August 2026.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima, Analia Gabriella Borges Ferraz Facury   +1 more
wiley   +1 more source

Impact of Gentamicin‐Impregnated Collagen Sponge on the Incidence of Access Related Infections After Full‐Support Microaxial Flow Pump Therapy

Artificial Organs, Volume 50, Issue 8, Page 1153-1163, August 2026.
Local application of gentamicin for wound closure after full‐support microaxial flow pump therapy. ABSTRACT Background Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential ...
Gaik Nersesian, Maximilian Rauch, Daniel Lewin, Leonard Pitts, Julius Kaemmel, Anna Stegmann, Julia Stein, Yuriy Hrytsyna, Felix Schoenrath, Volkmar Falk, Evgenij Potapov, Pia Lanmueller   +11 more
wiley   +1 more source

Characterization of Fosfomycin Resistant Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates from Human and Pig in Taiwan. [PDF]

PLoS ONE, 2015
To investigate the efficacy of fosfomycin against extended-spectrum β-lactamases (ESBL) producing Escherichia coli in Taiwan and the resistance mechanisms and characterization of human and pig isolates, we analyzed 145 ESBL-producing isolates collected ...
Sung-Pin Tseng, Sheng-Fan Wang, Cheng-Yu Kuo, Jun-Wei Huang, Wei-Chun Hung, Guan-Ming Ke, Po-Liang Lu   +6 more
doaj   +1 more source

Environmental Distribution of Pathogenic Leptospira spp. in Subtropical Rivers of Japan and Implications for Human Infection

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1073-1081, August 2026.
ABSTRACT Objectives Leptospirosis is a zoonotic disease caused by Leptospira spp. often linked to freshwater exposure in subtropical and tropical regions. Okinawa Prefecture reports the highest number of leptospirosis cases in Japan based on national surveillance data.
Atsuhiro Kanayama, Hiroko Ejiri, Yuki Chiko, Ikumi Namihira, Tomoki Yonaha, Kanetaka Kuba, Miyu Yoshimi, Nobuo Koizumi, Shigeto Takeshima, Koki Kaku   +9 more
wiley   +1 more source

Synergistic Effects from Combination of Cryptotanshinone and Fosfomycin Against Fosfomycin-Susceptible and Fosfomycin-Resistant Staphylococcus aureus

Infection and Drug Resistance, 2020
Zijing Ruan,1,* Jiaqi Cui,2,3,* Zhenqing He,2 Yuting Guo,2 Xu Jia,2 Xinhe Huang1 1School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, People’s Republic of China; 2Non-Coding RNA and Drug Discovery Key Laboratory
Ruan Z, Cui J, He Z, Guo Y, Jia X, Huang X   +5 more
doaj  

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

Global Distribution and Comparative Resistance Profiles of Escherichia coli Isolated From Bovine Meat and Meat Products: Evidence From Network Meta‐Analysis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic overview of the study and its principal findings. E. coli isolated from bovine meat and meat products was evaluated for antimicrobial resistance using Bayesian network meta‐analysis. The graphical abstract highlights the antimicrobial resistance ranking based on SUCRA, showing high resistance to penicillin, doxycycline, amoxicillin ...
Yaser Khorram Del, Peyman Mahmoudi, Amir Rashidi, Skala Idrees Hama Faraj, Jalal Rostamzadeh, Mohammad Razmkabir   +5 more
wiley   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi, Alphonse Charbel, Jan Pfeiffenberger, Uta Merle, Jessica Seessle, Theresa Wenz, Christa Flechtenmacher, Patrick Michl, Conrad Rauber   +8 more
wiley   +1 more source