Results 31 to 40 of about 22,313 (170)

Prevalence of fosfomycin resistance and mutations in murA, glpT, and uhpT in methicillin-resistant Staphylococcus aureus strains isolated from blood and cerebrospinal fluid samples

Frontiers in Microbiology, 2016
In China, fosfomycin alone or in combination with other antibiotics is commonly used in the treatment of infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Although fosfomycin-resistant S.
Zhuyingjie eFu, Ying eMa, Chunhui eChen, Yan eGuo, Fupin eHu, Yang eLiu, Xiaogang eXu, Minggui eWang   +7 more
doaj   +1 more source

Parenteral Fosfomycin in Gastrointestinal Surgery:A Systematic Review

, 2023
Background To investigate if perioperative parenteral administration of fosfomycin given before or during gastrointestinal surgery could protect against postoperative infectious complications and characterise the administration of fosfomycin and its ...
Fonnes, Masja Klindt, Holzknecht, Barbara Juliane, Fonnes, Siv, Rosenberg, Jacob   +3 more
core   +1 more source

Mechanisms of fosfomycin resistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2020
Objectives: Older antimicrobials such as fosfomycin are being considered as alternative agents in the treatment of drug-resistant organisms. However, there are limited data on the usefulness of fosfomycin against carbapenem-resistant Klebsiella ...
Peng Liu, Shuo Chen, Zhuo-ying Wu, Meng Qi, Xiang-yang Li, Cai-xia Liu   +5 more
doaj   +1 more source

Structural and Biochemical Insights into the Mechanism of Fosfomycin Phosphorylation by Fosfomycin Resistance Kinase FomA [PDF]

, 2011
We present here the crystal structures of fosfomycin resistance protein (FomA) complexed with MgATP, with ATP and fosfomycin, with MgADP and fosfomycin vanadate, with MgADP and the product of the enzymatic reaction, fosfomycin monophosphate, and with ADP
Svetlana Pakhomova, Bartlett, Sue G., Doerner, Pamela A, Pamela A. Doerner, Pakhomova, Svetlana, Newcomer, Marcia E, Sue G. Bartlett, Doerner, Pamela A., Bartlett, Sue G, Marcia E. Newcomer, Newcomer, Marcia E.   +10 more
core   +1 more source

High incidence of fosfomycin-resistant uropathogenic E. coli among children

BMC Infectious Diseases, 2023
Background There are few epidemiological or molecular data on Escherichia coli (E. coli) strains resistant to fosfomycin. In this study, we described the occurrence and characterization of fosfomycin-resistant uropathogenic E.
Wedad M. Abdelraheem, W. K.M Mahdi, Ibtehal S. Abuelela, Noha Anwar Hassuna   +3 more
doaj   +1 more source

Synergistic Combination of Linezolid and Fosfomycin Closing Each Other’s Mutant Selection Window to Prevent Enterococcal Resistance

Frontiers in Microbiology, 2021
Enterococci, the main pathogens associated with nosocomial infections, are resistant to many common antibacterial drugs including β-lactams, aminoglycosides, etc.
Lifang Jiang, Lifang Jiang, Na Xie, Na Xie, Mingtao Chen, Mingtao Chen, Yanyan Liu, Shuaishuai Wang, Shuaishuai Wang, Jun Mao, Jun Mao, Jiabin Li, Xiaohui Huang, Xiaohui Huang   +13 more
doaj   +1 more source

Mobile fosfomycin resistance genes in Enterobacteriaceae—An increasing threat [PDF]

, 2020
Antimicrobial resistance is one of the major threats to the health and welfare of both humans and animals. The shortage of new antimicrobial agents has led to the re-evaluation of old antibiotics such as fosfomycin as a potential regimen for treating ...
Schmitt, Kira; https://orcid.org/, Treier, Andrea, Zurfluh, Katrin; https://orcid.org/, Stephan, Roger; https://orcid.org/   +3 more
core   +1 more source

The Detection of Fosfomycin-Modifying Enzymes (fos) in Uropathogenic Enterobacterale, Azerbaijan, Iran

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
Enterobacteriaceae is the most common agent of urinary tract infections (UTIs). Multidrug resistant (MDR) and XDR (extensively drug-resistant) Enterobacteriaceae in UTIs have increased in the world.
Aidin Lalezadeh, Pardis Ghotaslou, Reza Ghotaslou   +2 more
doaj   +1 more source

Fosfomycin Enhances the Inhibition Ability of Linezolid Against Biofilms of Vancomycin-Resistant Enterococcus faecium in vitro

, 2023
Jie Chi,1 Yaowen Li,2,3 Na Zhang,2,3 Huiping Liu,2,3 Zhifeng Chen,1 Jiabin Li,4 Xiaohui Huang2,3 1Department of Pharmacy, Tongling Municipal Hospital, Tongling, Anhui, People’s Republic of China; 2Department of Basic and Clinical Pharmacology, School of ...
Liu H, Li Y, Li J, Chen Z, Huang X, Zhang N, Chi J   +6 more
core  

Efficacy of Fosfomycin against Planktonic and Biofilm-Associated MDR Uropathogenic Escherichia coli Clinical Isolates

Tropical Medicine and Infectious Disease, 2022
Urinary tract infections (UTI) are a severe public health problem and are caused mainly by the uropathogenic Escherichia coli (UPEC). Antimicrobial resistance and limited development of new antimicrobials have led to the reuse of old antibiotics such as ...
Haziel Eleazar Dzib-Baak, Andrés Humberto Uc-Cachón, Angel de Jesús Dzul-Beh, Rey Fernando Rosado-Manzano, Carlos Gracida-Osorno, Gloria María Molina-Salinas   +5 more
doaj   +1 more source