Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]
, 2019 BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk +4 more
core +1 more source
Synergistic Activity of Fosfomycin, Ciprofloxacin, and Gentamicin Against Escherichia coli and Pseudomonas aeruginosa Biofilms [PDF]
, 2019 Gram-negative (GN) rods cause about 10% periprosthetic joint infection (PJI) and represent an increasing challenge due to emergence of antimicrobial resistance.
Di Luca, Mariagrazia +4 more
core +1 more source
The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study. [PDF]
, 2020 BACKGROUND: In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common infections in children and adults.
Berger, C +5 more
core +3 more sources
Future Science OA, 2020 Aim: To evaluate the antibacterial activity of fosfomycin–meropenem and fosfomycin–colistin combinations against carbapenem-resistant Klebsiella pneumoniae (CR-Kp). Methods: A total of 50 CR-Kp isolates recovered from blood cultures were included in this
Yamuna Devi Bakthavatchalam +5 more
doaj +1 more source
The fosfomycin resistance gene fosB3 is located on a transferable, extrachromosomal circular intermediate in clinical Enterococcus faecium isolates. [PDF]
PLoS ONE, 2013 Some VanM-type vancomycin-resistant Enterococcus faecium isolates from China are also resistant to fosfomycin. To investigate the mechanism of fosfomycin resistance in these clinical isolates, antimicrobial susceptibility testing, filter-mating, Illumina/
Xiaogang Xu +7 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Objectives: This study investigated the synergistic in vitro and in vivo activity of cefazolin plus fosfomycin against methicillin-susceptible and methicillin-resistant S.
Manuel Kussmann +10 more
doaj +1 more source
Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4 [PDF]
, 2018 A putative fosA gene in Kluyvera georgiana 14751 showed 99% nucleotide identity with plasmid-encoded fosA4. Due to a single-nucleotide insertion translating to a truncated protein, K. georgiana 14751 fosA does not confer fosfomycin resistance.
Ghiglione, Barbara +4 more
core +1 more source
National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]
, 2016 From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L +3 more
core +1 more source
Successful Treatment of Acute Prostatitis Caused by Multidrug-Resistant Escherichia coli With Tigecycline Monotherapy [PDF]
, 2020 We present a successful treatment, with tigecycline monotherapy, of acute prostatitis caused by multidrug-resistant Escherichia coli harboring an NDM-1 carbapemenase along with a CMY-2 cephalosporinase and a TEM ...
Babouee Flury, Baharak +7 more
core +2 more sources
Infectious Diseases and Therapy, 2020 Introduction Severe pneumonia caused by multidrug-resistant Acinetobacter baumannii (MDR-AB) remains a difficult-to-treat infection. Considering the poor lung penetration of most antibiotics, the choice of the better antibiotic regimen is debated ...
Alessandro Russo +11 more
doaj +1 more source