Results 41 to 50 of about 17,034 (166)

Clinical Use of Intravenous Fosfomycin in Critical Care Patients in Taiwan

Pathogens, 2023
This retrospective study aimed to evaluate the clinical use and side effects of fosfomycin in critically ill patients in Taiwan. Forty-two patients (mean age, 69.9 years; female, 69%) who received fosfomycin were included from a teaching hospital in ...
Tzu-Ting Chen, Yun-Fu Chang, Yea-Chwen Wu   +2 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, Volume 13, Issue 44, 7 August 2026.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

High Prevalence and Overexpression of Fosfomycin-Resistant Gene fosX in Enterococcus faecium From China

Frontiers in Microbiology, 2022
Enterococci are one of the main causes of gastrointestinal tract infections in the healthcare system and can develop resistance to fosfomycin through plasmid or chromosomally encoded fosfomycin resistance genes.
Ling Xin, Ling Xin, Xiaogang Xu, Xiaogang Xu, Qingyu Shi, Qingyu Shi, Renru Han, Renru Han, Jue Wang, Jue Wang, Yan Guo, Yan Guo, Fupin Hu, Fupin Hu   +13 more
doaj   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons

JSFA reports, Volume 6, Issue 8, Page 314-330, August 2026.
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi, Khalil Guelift, Mokhtar Benmohamed, Khaled Kherraz, Latifa Khattabi, Afaf Khadra Bendrihem, Khaled Aggoun, Barbara Sawicka, Lilya Harchaoui, Mohamed Amine Ferhat, Salah Neghmouche Nacer, Stefania Garzoli   +11 more
wiley   +1 more source

Fosfomycin for Antibiotic Prophylaxis in Men Undergoing a Transrectal Prostate Biopsy: A Systematic Review and Meta-Analysis

Medicina, 2023
Background and Objectives: To assess the effects of fosfomycin compared with other antibiotics as a prophylaxis for urinary tract infections (UTIs) in men undergoing transrectal prostate biopsies. Materials and Methods: We searched multiple databases and
Hui Mo Gu, Jin Seok Gu, Ho Seok Chung, Seung Il Jung, Dongdeuk Kwon, Myung Ha Kim, Jae Hung Jung, Mi Ah Han, Seung Ji Kang, Eu Chang Hwang, Philipp Dahm   +10 more
doaj   +1 more source

Antimicrobial Resistance of Serratia marcescens Recovered From Aquatic Environments: A Review

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Serratia marcescens is a gram‐negative bacillus forming biofilms and showing multidrug resistance. Review (2019–2024) included 13 studies, 90 aquatic isolates. High resistance to β‐lactams, including carbapenems. Genes: blaOXA‐48, blaTEM‐1, aac(6′)‐Ic. Aquatic environments are reservoirs, requiring monitoring and control to prevent spread.
Heloisa Silva Inacio, Yasmim Raffaela Soares Santos, Magna Cristina de Paiva, Jaqueline Maria Siqueira Ferreira   +3 more
wiley   +1 more source

Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study

Annals of Clinical Microbiology and Antimicrobials, 2023
Background For treatment of ventriculitis, vancomycin and meropenem are frequently used as empiric treatment but cerebrospinal fluid (CSF) penetration is highly variable and may result in subtherapeutic concentrations.
Christina König, Jens Martens-Lobenhoffer, Patrick Czorlich, Manfred Westphal, Stefanie M. Bode-Böger, Stefan Kluge, Jörn Grensemann   +6 more
doaj   +1 more source

Efficacy of Fosfomycin and Its Combination With Aminoglycosides in an Experimental Sepsis Model by Carbapenemase-Producing Klebsiella pneumoniae Clinical Strains

Frontiers in Medicine, 2021
Carbapenemase-producing Klebsiella pneumoniae infections are an increasing global threat with scarce and uncertain treatment options. In this context, combination therapies are often used for these infections. The bactericidal and synergistic activity of
Tania Cebrero-Cangueiro, Tania Cebrero-Cangueiro, Tania Cebrero-Cangueiro, Gema Labrador-Herrera, Gema Labrador-Herrera, Álvaro Pascual, Álvaro Pascual, Álvaro Pascual, Caridad Díaz, Jesús Rodríguez-Baño, Jesús Rodríguez-Baño, Jesús Rodríguez-Baño, Jerónimo Pachón, Jerónimo Pachón, José P. del Palacio, María E. Pachón-Ibáñez, María E. Pachón-Ibáñez, M. Carmen Conejo   +17 more
doaj   +1 more source

Occurrence and Distribution of Environmental Pseudomonas aeruginosa From Hospitals in Bangladesh Reveals Diverse Strain Families, Multidrug Resistance, and Biofilm Formation

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Environmental reservoirs in Bangladeshi hospitals harbor phylogenetically diverse, multidrug‐resistant Pseudomonas aeruginosa with extensive biofilm‐forming capacity and class 1 integron‐associated resistance genes. These findings highlight hospital environments as persistent sources of antimicrobial resistance dissemination and underscore the need for
S. M. Kador, Tanay Chakrovarty, Khandaker Adil, Md. Mustak Ahmed, Md. Mohsin Kobir, Md. Hasanuzzaman, Mousufa Akter, Tanzima Sharmim Taowhid, Md. Tanvir Islam, Ovinu Kibria Islam   +9 more
wiley   +1 more source