Results 61 to 70 of about 22,313 (170)

Mutations of the Transporter Proteins GlpT and UhpT Confer Fosfomycin Resistance in Staphylococcus aureus

Frontiers in Microbiology, 2017
With the increasing spread of methicillin-resistant Staphylococcus aureus worldwide, fosfomycin has begun to be used more often, either alone or in combination with other antibiotics, for treating methicillin-resistant S.
Su Xu, Su Xu, Zhuyingjie Fu, Zhuyingjie Fu, Ying Zhou, Ying Zhou, Yang Liu, Yang Liu, Xiaogang Xu, Xiaogang Xu, Minggui Wang, Minggui Wang   +11 more
doaj   +1 more source

Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study

Annals of Clinical Microbiology and Antimicrobials, 2023
Background For treatment of ventriculitis, vancomycin and meropenem are frequently used as empiric treatment but cerebrospinal fluid (CSF) penetration is highly variable and may result in subtherapeutic concentrations.
Christina König, Jens Martens-Lobenhoffer, Patrick Czorlich, Manfred Westphal, Stefanie M. Bode-Böger, Stefan Kluge, Jörn Grensemann   +6 more
doaj   +1 more source

Characterization of Fosfomycin Resistant Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates from Human and Pig in Taiwan. [PDF]

PLoS ONE, 2015
To investigate the efficacy of fosfomycin against extended-spectrum β-lactamases (ESBL) producing Escherichia coli in Taiwan and the resistance mechanisms and characterization of human and pig isolates, we analyzed 145 ESBL-producing isolates collected ...
Sung-Pin Tseng, Sheng-Fan Wang, Cheng-Yu Kuo, Jun-Wei Huang, Wei-Chun Hung, Guan-Ming Ke, Po-Liang Lu   +6 more
doaj   +1 more source

Efficacy of Fosfomycin and Its Combination With Aminoglycosides in an Experimental Sepsis Model by Carbapenemase-Producing Klebsiella pneumoniae Clinical Strains

Frontiers in Medicine, 2021
Carbapenemase-producing Klebsiella pneumoniae infections are an increasing global threat with scarce and uncertain treatment options. In this context, combination therapies are often used for these infections. The bactericidal and synergistic activity of
Tania Cebrero-Cangueiro, Tania Cebrero-Cangueiro, Tania Cebrero-Cangueiro, Gema Labrador-Herrera, Gema Labrador-Herrera, Álvaro Pascual, Álvaro Pascual, Álvaro Pascual, Caridad Díaz, Jesús Rodríguez-Baño, Jesús Rodríguez-Baño, Jesús Rodríguez-Baño, Jerónimo Pachón, Jerónimo Pachón, José P. del Palacio, María E. Pachón-Ibáñez, María E. Pachón-Ibáñez, M. Carmen Conejo   +17 more
doaj   +1 more source

Antibiotic Use for Cystitis and Risk of Treatment Failure in Pregnancy Following Gastric Bypass: A Cohort Study

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Cystitis is common during pregnancy and requires effective antibiotic treatment to prevent complications. Gastric bypass surgery alters gastrointestinal anatomy and may impair oral drug absorption, raising concerns about antibiotic effectiveness.
Mette Østergaard Thunbo, Line Kolding, Samuel Azuz, Terese Matthesen Kamronn, Lene Høimark, Lars Henning Pedersen   +5 more
wiley   +1 more source

Genetic Diversity and Epidemiological Overlap of Staphylococcus aureus at the Animal–Food–Environment–Human Interface Within a One Health Framework

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Integrating farm‐to‐fork and clinical surveillance, this study reveals distinct SCCmec distributions alongside shared spa types across human, animal, and food interfaces. The results of genetic diversity and epidemiological overlap underscore the critical need for coordinated One Health surveillance to monitor multi‐sectoral Staphylococcus aureus ...
Pinar Sagiroglu, Dursun Alp Gundog, Candan Gungor, Kursat Koskeroglu, Mustafa Altay Atalay, Adalet Dishan, Yeliz Ucar, Aytac Akcay, Huseyin Burak Disli, Harun Hizlisoy, Mukaddes Barel, Tekin Kececi, Nurhan Ertas Onmaz   +12 more
wiley   +1 more source

Synergistic Effects from Combination of Cryptotanshinone and Fosfomycin Against Fosfomycin-Susceptible and Fosfomycin-Resistant Staphylococcus aureus

Infection and Drug Resistance, 2020
Zijing Ruan,1,* Jiaqi Cui,2,3,* Zhenqing He,2 Yuting Guo,2 Xu Jia,2 Xinhe Huang1 1School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, People’s Republic of China; 2Non-Coding RNA and Drug Discovery Key Laboratory
Ruan Z, Cui J, He Z, Guo Y, Jia X, Huang X   +5 more
doaj  

Antibiotic Resistance and Biofilm‐Forming Capacity of Oral Biofilm Bacteria in Patients With Periodontitis and Healthy Individuals

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Key finding: Antimicrobial resistance was common across all groups and associated with biofilm‐forming capacity, an association that remains observational and species‐confounded. ABSTRACT This study aimed to analyse antimicrobial resistance (AMR) in bacterial isolates from subgingival biofilms of patients with periodontitis and supragingival biofilms ...
Nils Werner, Marie Schöffel, Annette Wittmer, Klaus Pelz, Kirstin Vach, Cornelia Frese, Christiane von Ohle, Diana Wolff, Fabian Cieplik, Ali Al‐Ahmad   +9 more
wiley   +1 more source

First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman, Rafid Muntasir Ul Azam, Md. Sazib Hossain, Samina Momtaz, Anowara Begum, Munawar Sultana   +5 more
wiley   +1 more source

Fosfomycin Resistance in Escherichia coli, Pennsylvania, USA

, 2015
Fosfomycin resistance in Escherichia coli is rare in the United States. An extended-spectrum β-lactamase–producing E. coli clinical strain identified in Pennsylvania, USA, showed high-level fosfomycin resistance caused by the fosA3 gene.
Sangeeta Sastry, Caressa N. Spychala, Yohei Doi, Hind Alrowais, Adeel A. Butt, Qinglan Guo, Christi L. McElheny   +6 more
core   +1 more source