Candidemia: Evolution of Drug Resistance and Novel Therapeutic Approaches
Infection and Drug Resistance, 2021 Anna Maria Tortorano,1 Anna Prigitano,1 Gianluca Morroni,2 Lucia Brescini,2,3 Francesco Barchiesi2,4 1Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milano, Italy; 2Department of Biomedical Sciences and Public Health ...
Tortorano AM +4 more
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Effect of Star Topology Versus Linear Polymers on Antifungal Activity and Mammalian Cell Toxicity
Macromolecular Bioscience, Volume 24, Issue 5, May 2024.Synthetic polymers inspired by natural antimicrobial peptides have shown promise for the treatment of fungal infections. The present study compares linear to star‐like topology of amphiphilic, positively charged polymers. A low‐Xn 3‐arm polymer shows favourable activity against Candida spp. and biocompatibility with fibroblasts.
Sebastian Schaefer +4 more
wiley +1 more source
What is the role of microbial biotechnology and genetic engineering in medicine?
MicrobiologyOpen, Volume 13, Issue 2, April 2024.Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
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New and emerging options for management of invasive fungal diseases in paediatric patients
Mycoses, Volume 67, Issue 1, January 2024.Abstract Invasive fungal diseases (IFDs) play an important role in the supportive care of paediatric patients with acute leukaemia and those undergoing allogeneic haematopoietic cell transplantation, and they are associated with significantly decreased overall survival rates in affected individuals.
Andreas H. Groll +3 more
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Candidemia: An Update on Epidemiology, Risk Factors, Diagnosis, Susceptibility, and Treatment
PathogensCandidemia is a highly prevalent invasive fungal infection caused primarily by C. albicans, C. parapsilosis, C. glabrata (currently Nakaseomyces glabratus), C. tropicalis, and C. krusei (currently Pichia kudriavzevii). Risk factors for the development of
Juan Pablo Cabrera-Guerrero +7 more
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Update on therapeutic approaches for invasive fungal infections in adults
Therapeutic Advances in Infectious DiseaseInvasive fungal infections are increasingly encountered with the expansion of iatrogenic immunosuppression, including not only solid organ and hematopoietic stem cell transplant recipients but also patients with malignancies or autoimmune diseases ...
Catherine-Audrey Boutin, Me-Linh Luong
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New treatment options for critically important WHO fungal priority pathogens.
Clinical Microbiology and InfectionBACKGROUND Yet often overlooked in public health discourse, fungal infections pose a crucialglobal disease burden associated with annual mortality rates approximately equal to tuberculosis and HIV.
Lisa Kriegl +4 more
semanticscholar +1 more source
When Should Clinical Mycology Laboratories Perform Antifungal Susceptibility Testing? Revisiting Practice Through the Lens of Intrinsic Resistance. [PDF]
MycopathologiaLass-Flörl C, Arikan-Akdagli S.
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Disseminated Musculoskeletal Coccidioidomycosis in an Immunocompetent Host: A Rare Case Requiring Extensive Spinal and Pelvic Surgery. [PDF]
CureusRaman E, Sharma S.
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The looming threat of invasive fungal infections in heart transplant recipients: Will it be the last of us. [PDF]
JHLT OpenLowe A, King ST, Hand J.
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