Clinical Mycology Today: Emerging challenges and opportunities [PDF]
The Mycoses Study Group Education and Research Consortium is a collective of clinicians, researchers, and educators with the common goal to advance awareness, diagnosis, and management of invasive fungal diseases.
Little, Jessica +7 more
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Investigation of a Lomentospora prolificans case cluster with whole genome sequencing [PDF]
, 2020 Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates
Boan, P. +5 more
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Epidemiologia, biologia, resistência a antifúngicos e virulência do fungo emergente Candida auris: Epidemiology, biology, antifungal resistance and virulence of the emerging fungus Candida auris [PDF]
, 2022 Introdução: A Candida auris é uma nova espécie de patógeno fúngico altamente resistente e emergente que causa infecções invasivas graves. O objetivo desse estudo é realizar um levantamento sobre o gênero Candida, destacando características gerais ...
de Barros, Neuza Biguinati +2 more
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Towards covalent inhibition of phosphoglucomutase in Aspergillus fumigatus [PDF]
, 2023 Kowalski, Bartosz
core +1 more source
Candida Auris Features and its Treatment: Global Emergency [PDF]
Fungal pathogen Candida auris was identified in 2009, in Japan. Currently, it is identified in 5 continents, in more than 40 countries. Therefore, it is nowadays defined as critical priority pathogen.
Durán, Nelson +2 more
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Molecular architecture of chitin and chitosan-dominated cell walls in zygomycetous fungal pathogens by solid-state NMR [PDF]
Zygomycetous fungal infections pose an emerging medical threat among individuals with compromised immunity and metabolic abnormalities. Our pathophysiological understanding of these infections, particularly the role of fungal cell walls in growth and ...
Ankur, Ankur +6 more
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Antimicrobial Agents and ChemotherapyABSTRACT Immunocompromised patients are susceptible to fungal infections, and drug-drug interactions with antifungals may occur due to concomitant medications. Fosmanogepix [FMGX; active moiety manogepix (MGX)] targets glycosylphosphatidylinositol-anchored mannoprotein synthesis and maturation ...
Michael R. Hodges +5 more
openaire +2 more sources
New preparations in systemic fungal infections [PDF]
Introducere Infecțiile fungice sistemice (invazive) reprezintă o problemă medicală și de sănătate publică majoră în ultimele două decenii. S-a estimat că, la nivel global, 1-1,2 miliarde de persoane sunt afectate de fungi, cu aproximativ 1,5 milioane ...
Bacinschi, Nicolae +2 more
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Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B. [PDF]
Ibrexafungerp (formerly SCY-078) is the first member of the triterpenoid class that prevents the synthesis of the fungal cell wall polymer β-(1,3)-D-glucan by inhibiting the enzyme glucan synthase.
Alkhazraji, Sondus +8 more
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Azole resistance in Aspergillus fumigatus is a One Health resistance threat, where azole fungicide exposure compromises the efficacy of medical azoles. The use of the recently authorized fungicide ipflufenoquin, which shares its mode-of-action with a new
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