Results 101 to 110 of about 848 (155)

Faculty Opinions recommendation of The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021
openaire   +2 more sources

Identification of antifungal agents AR-12 and Fosmanogepix as anti-Trypanosoma cruzi drugs through an enhanced fluorogenic β-galactosidase phenotypic screening assay

ABSTRACT Phenotypic screening remains essential for identifying and characterizing bioactive compounds or their combinations against human parasitic pathogens. In the case of Trypanosoma cruzi, the etiological agent of Chagas disease, transgenic parasites expressing the reporter enzyme β-galactosidase have been extensively used to this end.
Mercedes Didier Garnham, Franco Agustín Agüero, Juan Carlos Ramírez, Fernán Agüero, Emir Salas-Sarduy   +4 more
openaire   +1 more source

When Should Clinical Mycology Laboratories Perform Antifungal Susceptibility Testing? Revisiting Practice Through the Lens of Intrinsic Resistance. [PDF]

Mycopathologia
Lass-Flörl C, Arikan-Akdagli S.
europepmc   +1 more source

Novel Inositol Acyltransferase (Gwt1) Inhibitor for Fungal Keratitis Treatment: Evaluation of In Vitro and In Vivo Efficacy and Safety. [PDF]

Invest Ophthalmol Vis Sci
Gowtham L, Meghana Y, Mannangatty T, Vasavi S, Nirmal J, Bagga B, Garg P, Mishra DK, Roy S.   +8 more
europepmc   +1 more source

Disseminated Musculoskeletal Coccidioidomycosis in an Immunocompetent Host: A Rare Case Requiring Extensive Spinal and Pelvic Surgery. [PDF]

Cureus
Raman E, Sharma S.
europepmc   +1 more source

The looming threat of invasive fungal infections in heart transplant recipients: Will it be the last of us. [PDF]

JHLT Open
Lowe A, King ST, Hand J.
europepmc   +1 more source

Comprehensive strategies to defeat Candida auris - challenge and insight: A review. [PDF]

Medicine (Baltimore)
Zhang J, Zhong L, Chen C, Ye L, Cao F, Xia H, Hong Y.   +6 more
europepmc   +1 more source

Cerebral Aspergillosis: Diagnostic Challenges, Therapeutic Strategies, and Future Research. [PDF]

CNS Drugs
Chantelot L, Sitterlé E, Poirée S, Jullien V, Danion F, Serris A.   +5 more
europepmc   +1 more source

Virtual screening assisted identification of a phytocompound as potent inhibitor against Candida lusitaniae; an in-silico study. [PDF]

BMC Infect Dis
Timotheous R, Naz H, Arif U, Dar MT, Sarwar MF, Awan MF, Ali S, Rab SO.   +7 more
europepmc   +1 more source

Antifungal Drugs for the Treatment of Invasive Fungal Infections-A Limited Therapeutic Toolbox Facing Growing Resistances. [PDF]

Pharmaceuticals (Basel)
Susan V, Lang M, Sabou M, Bourel-Bonnet L.   +3 more
europepmc   +1 more source