Results 181 to 190 of about 74,468 (287)

A General Workflow for Tangential Flow Filtration Perfusion Scale‐Up

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) perfusion using hollow‐fiber modules offers substantial advantages over other mammalian cell retention technologies. Recently, increased awareness of Starling flow has helped to enhance filtration performance to similar, or even higher levels compared to alternative technologies.
Patrick Romann, Ken Lee, Venkatesh Natarajan, Daniel Ley, Claes Nymand Nilsson, David Garcia‐Munzer, Dominik Schieman, Mahbod Hajighasemi, Alex Zaytsev, Jason Friedman, Loic Chappuis, Tobias Habicher, Colin Jaques, Alex Cohen, Matthew Gagnon, Edward Chan, Daniel J. Karst, Philip Giller, Antony Sibilia, Andrew L. Zydney, Thomas K. Villiger   +20 more
wiley   +1 more source

Membrane Distillation: Module Design and Application Performance. [PDF]

Membranes (Basel)
Nthunya LN, Mamba BB.
europepmc   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Polymer Microfiltration and Ultrafiltration Membranes Containing Inorganic Modifiers: Functional Properties and Performance-Review. [PDF]

Polymers (Basel)
Dzyazko YS, Chmilenko VV, Pini Pereira P, Rozhdestvenska LM, Kudelko KO, Novelli do Nascimento N, Marquetotti Salcedo Vieira A, Nishi L, Bergamasco R.   +8 more
europepmc   +1 more source

Mechanistic Analysis of Drug Linker Clearance During Ultrafiltration/Diafiltration of an Antibody–Drug Conjugate

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Ultrafiltration/diafiltration (UF/DF) is a key unit operation in the manufacture of antibody‐drug conjugates (ADCs), commonly utilized for post‐conjugation purification to remove residual Drug Linker (DL) compounds and affect buffer exchange.
Vasudev Tangry, Fara Lyu, Amy Le, Laurie Mlinar, Manish S. Kelkar, Andrew L. Zydney   +5 more
wiley   +1 more source

Vibrating membrane bioreactors enhance nutrient removal and energy efficiency in municipal wastewater treatment. [PDF]

Nat Commun
Lin W, Xue T, Ding H, Liu Z, Zhang C, Xiao K, Chen C, Huang X.   +7 more
europepmc   +1 more source

Microfiltration (MF) and Ultrafiltration (UF) for Sewage and Surface Water Concentration for SARS‐CoV‐2 and Other Enveloped Viruses' Detection in Wastewater‐Based Epidemiology (WBE)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT This study objective was to evaluate hollow fiber membranes for concentration of enveloped enteric viruses in sewage and surface water samples. Microfiltration (MF, 0.2 µm nominal pore size) and ultrafiltration (UF, 100 kDa molecular weight cut‐off) hollow fiber membranes were compared for the concentration of the bovine respiratory syncytial ...
Rodrigo Almeria Ragio, Rodrigo de Freitas Bueno, Roseli Frederigi Benassi, Eduardo Lucas Subtil   +3 more
wiley   +1 more source

iEVIP: a dual-inspired intelligent platform for smart response extracellular vesicle isolation and single-vesicle profiling. [PDF]

Nat Commun
Xie H, Chen T, Yan P, Fu Y, Lei M, Liu Y, Zhao X, Du W, Feng X, Liu X, Li Y, Chen P, Liu BF.   +12 more
europepmc   +1 more source

Process Analytical Technology (PAT) for Continuous Purification of mRNA via Precipitation and Tangential Flow Filtration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Continuous downstream processing of messenger ribonucleic acid (mRNA) therapeutics requires purification strategies that are scalable, robust, and capable of removing product‐ and process‐related impurities from in vitro transcription mixtures.
Rajan R. Bhawnani, Maria del Carme Pons Royo, Rohan Kadambi, Andrew Hatas, Steve Burcat, Tyler Arnold, Hasan Al‐Mahayni, Richard D. Braatz, Allan S. Myerson   +8 more
wiley   +1 more source