Results 101 to 110 of about 4,690,912 (308)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Further evidence on the link between health care spending and health outcomes in England [PDF]

This report describes results from research funded by the Health Foundation under its Quest for Quality and Improved Performance (QQuIP) initiative. It builds on our earlier report for the Health Foundation – The link between health care spending and ...
Nigel Rice, Peter C Smith, Stephen Martin   +2 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Open Learning Network: the evidence of OER impact [PDF]

, 2010
Much of the initial work on Open Educational Resources (OER) has inevitably concentrated on how to produce the resources themselves and to establish the idea in the community.
Cropper, Karen, McAndrew, Patrick
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation

Health Technology Assessment, 2016
Background: End-stage renal disease is a long-term irreversible decline in kidney function requiring kidney transplantation, haemodialysis or peritoneal dialysis.
Marcela Haasova, Tristan Snowsill, Tracey Jones-Hughes, Louise Crathorne, Chris Cooper, Jo Varley-Campbell, Ruben Mujica-Mota, Helen Coelho, Nicola Huxley, Jenny Lowe, Jan Dudley, Stephen Marks, Chris Hyde, Mary Bond, Rob Anderson   +14 more
doaj   +1 more source

Total Joint Registries: A Foundation for Evidence-Based Arthroplasty

AMA Journal of Ethics, 2010
An argument that national joint registries have improved outcomes for arthroplasty patients because they track device performance, reduce revision surgeries, and promote evidence-based surgery. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
Fabian, von Knoch, Anthony, Marchie, Henrik, Malchau   +2 more
openaire   +2 more sources

Brief of Amici Curiae in Support of Appellant, James Townsend v. Midland Funding, LLC [PDF]

, 2013
The Consumer Protection Clinic of the University of Maryland Francis King Carey School of Law, filed a Motion to Participate and an Amicus Brief in the case of Townsend v. Midland Funding, LLC.
Cohen, Stuart Robert, Holland, Peter A.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Developing an integrated depression and tuberculosis care pathway using a co-design approach in a low-resource setting

International Journal of Mental Health Systems
Background Evidence suggests the use of a participatory approach for the improvement of TB care, however, there is limited evidence on how integrated depression screening and care could be delivered with TB services.
Olamide Todowede, Zara Nisar, Saima Afaq, Sushama Kanan, Aliya Ayub, Rumana Huque, Akhtar Hussain, Mudasser Shehzad, Najma Siddiqi   +8 more
doaj   +1 more source