Results 111 to 120 of about 4,690,912 (308)
Effective Philanthropy: The Importance Of Focus [PDF]
, 2002 Generosity doesn't always translate into results. The reality is that not all grantmaking is effective. What are the prerequisites to effective philanthropy?
Richard A. Mittenthal
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
294 ACUPUNCTURE FOR OVERACTIVE BLADDER IN ADULTS: A COCHRANE REVIEW
Continence, 2022 E Hargreaves +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Are Foundation Leaders Using Social Media? [PDF]
, 2010 All it takes is a quick visit to Glasspockets.org to see just how fast and how far foundations have come in terms of using social media. As of August 2010, the web site had documented the Web 2.0 activities of more than 650 foundations, including 271 ...
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Foundations of Evidence-Based Medicine [PDF]
JAMA: The Journal of the American Medical Association, 2003 +4 more sources
The Value of Evidence-Based Computer Simulation of Oral Health Outcomes for Management Analysis of the Alaska Dental Health Aide Program [PDF]
, 2008 Objectives: To create an evidence‐based research tool to inform and guide policy and program managers as they develop and deploy new service delivery models for oral disease prevention and intervention.
Haley, Sharman +3 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Child Abuse Programme: What We're Learning November 2011 [PDF]
, 2011 For the Child Abuse Programme, learning is not an isolated function or an end in itself. Learning is one of the strategies through which Oak Foundation can support improvements in programming and policy-making in the field of child sexual abuse and ...
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