Results 211 to 220 of about 8,780,344 (351)

No evidence for genetic role of the tumor necrosis factor pathway in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Shahkhali MG, Liu L, Somerville EN, Noyce AJ, Gan-Or Z, Senkevich K.   +5 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Developing Topics. [PDF]

Alzheimers Dement
Blasco D.
europepmc   +1 more source

Foundational Papers: Strengthening Clinical Research Proposals Through Pre-Grant Evidence Building

Ricardo Pietrobon, Aline Machiavelli, Liliana Rodrigues, Amit Agrey, Lizzy Nkeangnyi, Victor Galvão, Lucas Teixeira   +6 more
openalex   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Serum ferritin level and morbidity risk in transfusion-independent patients with β-thalassemia intermedia: the ORIENT study

Haematologica, 2014
Khaled M. Musallam, Maria Domenica Cappellini, Shahina Daar, Mehran Karimi, Amal El-Beshlawy, Giovanna Graziadei, Matthew Magestro, Jerome Wulff, Guilhem Pietri, Ali T. Taher   +9 more
doaj   +1 more source

Consensus-based guidelines on subtrochanteric femur fractures: Bridging evidence and experience on 11 key clinical dilemmas. [PDF]

SICOT J
Keny S, Sharma G, Poduval M, Tiwari A, Bagaria V.   +4 more
europepmc   +1 more source

CopilotCAD: Empowering Radiologists with Report Completion Models and Quantitative Evidence from Medical Image Foundation Models [PDF]

Sheng Wang, Tianming Du, Katherine Fischer, Gregory E. Tasian, Justin B. Ziemba, Joanie M. Garratt, Hersh Sagreiya, Yong Fan   +7 more
openalex   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source